K Nishioka Selected Research

Osteoarthritis

1/2007	Effects of celecoxib on human chondrocytes--enhanced production of chemokines.
8/2005	The role of subchondral bone resorption pits in osteoarthritis: MMP production by cells derived from bone marrow.
1/2005	Chemokines differentially induce matrix metalloproteinase-3 and prostaglandin E2 in human articular chondrocytes.
5/2004	Effects of glucosamine hydrochloride on the production of prostaglandin E2, nitric oxide and metalloproteases by chondrocytes and synoviocytes in osteoarthritis.
2/2003	Presence of pannus-like tissue on osteoarthritic cartilage and its histological character.
7/2001	Autoantibodies to osteopontin in patients with osteoarthritis and rheumatoid arthritis.
7/2001	Infection of synoviocytes with HTLV-I induces telomerase activity.
5/2001	Potential role of HOXD9 in synoviocyte proliferation.
5/2001	The role of C-C chemokines and their receptors in osteoarthritis.
4/2001	Implication of cartilage intermediate layer protein in cartilage destruction in subsets of patients with osteoarthritis and rheumatoid arthritis.

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K Nishioka Research Topics

Disease

19	Rheumatoid Arthritis 03/2011 - 01/2000
11	Osteoarthritis 01/2007 - 04/2000
10	Contact Dermatitis (Eczema, Contact) 12/2004 - 02/2000
6	Neoplasms (Cancer) 01/2017 - 01/2000
6	Necrosis 01/2014 - 01/2000
6	Joint Diseases (Joint Disease) 01/2014 - 04/2000
5	Psoriasis (Pustulosis Palmaris et Plantaris) 10/2006 - 07/2000
5	Arthritis (Polyarthritis) 05/2005 - 04/2001
4	Hyperplasia 01/2014 - 03/2000
4	Neoplasm Metastasis (Metastasis) 01/2007 - 01/2000
4	Sclerosis 03/2005 - 11/2000
4	Atopic Dermatitis (Atopic Eczema) 12/2004 - 06/2000
4	Autoimmune Diseases (Autoimmune Disease) 04/2001 - 04/2000
4	Systemic Lupus Erythematosus (Libman-Sacks Disease) 02/2001 - 08/2000
2	Carcinogenesis 01/2017 - 01/2000
2	Bone Resorption 08/2005 - 11/2004
2	Drug Eruptions (Drug Eruption) 05/2005 - 09/2001
2	Hypersensitivity (Allergy) 05/2005 - 11/2000
2	Synovitis 11/2004 - 07/2000
2	Allergic Contact Dermatitis 09/2001 - 02/2001
2	Infections 07/2001 - 04/2000
2	Insulin Resistance 07/2001 - 03/2001
2	Behcet Syndrome (Behcet's Syndrome) 01/2001 - 08/2000
2	Systemic Scleroderma (Systemic Sclerosis) 01/2001 - 11/2000
2	Eosinophilia 12/2000 - 08/2000
2	Stomach Neoplasms (Stomach Cancer) 08/2000 - 01/2000
2	Hepatitis 04/2000 - 01/2000
1	Breast Neoplasms (Breast Cancer) 01/2017
1	Carcinoma (Carcinomatosis) 01/2007
1	Esophageal Neoplasms (Esophageal Cancer) 01/2007
1	Twenty-Nail Dystrophy 05/2005
1	Lichen Planus (Lichen Ruber Planus) 05/2005
1	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 06/2004
1	Fibrosis (Cirrhosis) 01/2004
1	Retinoblastoma (Glioblastoma, Retinal) 09/2003
1	Hepatitis B 05/2003

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 03/2004 - 01/2001
5	CytokinesIBA 06/2003 - 08/2000
5	AntigensIBA 10/2002 - 04/2000
5	AutoantibodiesIBA 07/2001 - 11/2000
4	AntibodiesIBA 01/2017 - 11/2000
4	Bleomycin (Blenoxane)FDA LinkGeneric 03/2005 - 11/2000
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2004 - 03/2000
4	EnzymesIBA 01/2001 - 01/2000
3	Matrix Metalloproteinases (MMPs)IBA 01/2007 - 05/2005
3	ChemokinesIBA 01/2005 - 05/2001
3	Immunoglobulin E (IgE)IBA 12/2004 - 11/2001
3	Telomerase (Telomerase Reverse Transcriptase)IBA 09/2003 - 01/2000
3	EpitopesIBA 04/2001 - 11/2000
3	Stem Cell FactorIBA 01/2001 - 11/2000
2	Transcription Factors (Transcription Factor)IBA 01/2017 - 01/2000
2	anti-Fas monoclonal antibodyIBA 01/2014 - 04/2000
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2007 - 05/2004
2	Tacrolimus (Prograf)FDA LinkGeneric 10/2006 - 11/2000
2	Interleukin-18 (Interleukin 18)IBA 05/2005 - 11/2004
2	ElementsIBA 12/2004 - 12/2004
2	InterleukinsIBA 11/2004 - 09/2000
2	Messenger RNA (mRNA)IBA 01/2004 - 04/2000
2	Complementary DNA (cDNA)IBA 01/2004 - 05/2001
2	4-phenylenediamine (p-phenylenediamine)FDA Link 06/2003 - 09/2001
2	Tuberculin (PPD)IBA 06/2003 - 09/2001
2	Hepatitis B Surface Antigens (HBsAg)FDA Link 05/2003 - 06/2000
2	Anthralin (Dithranol)IBA 01/2003 - 07/2000
2	Fas Ligand Protein (Fas Ligand)IBA 01/2003 - 03/2000
2	Chemokine ReceptorsIBA 12/2001 - 05/2001
2	Irritants (Vesicants)IBA 11/2001 - 03/2001
2	CholesterolIBA 07/2001 - 03/2001
2	AutoantigensIBA 04/2001 - 01/2001
2	ImmunosorbentsIBA 01/2001 - 12/2000
2	Interleukin-5 (Interleukin 5)IBA 12/2000 - 08/2000
1	Insulin-Like PeptidesIBA 01/2017
1	Monoclonal AntibodiesIBA 01/2014
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2014
1	tocilizumab (atlizumab)FDA Link 03/2011
1	Celecoxib (Celebrex)FDA Link 01/2007
1	Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)IBA 01/2007
1	Chemokine CCL5IBA 01/2007
1	GoldIBA 05/2005
1	roxatidine acetate (roxatidine)IBA 05/2005
1	Plasminogen Activator Inhibitor 1IBA 03/2005
1	Fibrinolysin FDA Link 03/2005
1	ProstaglandinsIBA 01/2005
1	Interleukin-4 (Interleukin 4)IBA 12/2004
1	Interleukin-13IBA 12/2004
1	matrigelIBA 06/2004
1	Metalloproteases (Metalloproteinases)IBA 05/2004
1	Dinoprostone (PGE2)FDA Link 05/2004
1	Glucosamine (Dona)IBA 05/2004
1	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 03/2004
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 01/2004
1	Retinoblastoma ProteinIBA 09/2003
1	CyclinsIBA 09/2003
1	Minocycline (Cyclops)FDA LinkGeneric 05/2003
1	safranine T (safranin)IBA 02/2003
1	CryoglobulinsIBA 01/2003

Therapy/Procedure

10	Therapeutics 01/2004 - 03/2000
1	Esophagectomy 01/2007
1	Replacement Arthroplasty 01/2005
1	Knee Replacement Arthroplasty (Total Knee Replacement) 05/2004
1	Arthroplasty 02/2003