Iain B McInnes Selected Research

Interleukin-17 (Interleukin 17)

3/2024	EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2023 update.
2/2024	Association of the clinical components in the distal interphalangeal joint synovio-entheseal complex and subsequent response to ixekizumab or adalimumab in psoriatic arthritis.
1/2023	Bimekizumab in patients with psoriatic arthritis, naive to biologic treatment: a randomised, double-blind, placebo-controlled, phase 3 trial (BE OPTIMAL).
1/2023	Bimekizumab in patients with active psoriatic arthritis and previous inadequate response or intolerance to tumour necrosis factor-α inhibitors: a randomised, double-blind, placebo-controlled, phase 3 trial (BE COMPLETE).
1/2023	Optimising psoriatic arthritis therapy with immunological methods to increase standard evaluation: the protocol of an open-label multicentre, parallel-group, two-arm randomised controlled study evaluation precision medicine approach in the treatment of psoriatic arthritis.
1/2022	A review of JAK-STAT signalling in the pathogenesis of spondyloarthritis and the role of JAK inhibition.
1/2022	Targeted systemic therapies for psoriatic arthritis: a systematic review and comparative synthesis of short-term articular, dermatological, enthesitis and dactylitis outcomes.
10/2021	IL-23 orchestrating immune cell activation in arthritis.
1/2021	Comparative effectiveness of guselkumab in psoriatic arthritis: results from systematic literature review and network meta-analysis.
1/2021	Translational targeting of inflammation and fibrosis in frozen shoulder: Molecular dissection of the T cell/IL-17A axis.

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Iain B McInnes Research Topics

Disease

103	Psoriatic Arthritis 03/2024 - 03/2007
103	Rheumatoid Arthritis 02/2024 - 05/2002
62	Inflammation (Inflammations) 08/2023 - 05/2002
51	Psoriasis (Pustulosis Palmaris et Plantaris) 03/2024 - 08/2004
51	Arthritis (Polyarthritis) 03/2024 - 12/2002
33	Necrosis 02/2024 - 01/2006
19	Infections 11/2023 - 02/2003
19	Experimental Arthritis 08/2023 - 12/2002
15	Pain (Aches) 03/2024 - 05/2013
14	Ankylosing Spondylitis 11/2023 - 01/2016
14	Autoimmune Diseases (Autoimmune Disease) 01/2023 - 02/2003
12	Synovitis 02/2024 - 05/2002
10	Rheumatic Diseases (Rheumatism) 01/2023 - 10/2006
9	Joint Diseases (Joint Disease) 02/2024 - 08/2008
9	Tendinopathy (Tendonitis) 01/2021 - 10/2010
8	COVID-19 01/2023 - 01/2020
7	Fatigue 03/2024 - 12/2018
7	Disease Progression 12/2023 - 12/2007
6	Atherosclerosis 06/2015 - 02/2008
5	Chronic Disease (Chronic Diseases) 03/2024 - 08/2011
5	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2024 - 01/2019
5	Axial Spondyloarthritis 12/2023 - 01/2019
5	Musculoskeletal Diseases (Musculoskeletal Disease) 01/2022 - 07/2017
5	Myocardial Infarction 01/2019 - 01/2010
5	Osteoarthritis 01/2018 - 11/2010
4	Neoplasms (Cancer) 05/2024 - 02/2003
4	Cytokine Release Syndrome 12/2023 - 01/2020
4	Herpes Zoster 02/2023 - 12/2018
4	Hypoxia (Hypoxemia) 01/2020 - 02/2012
3	Hypertension (High Blood Pressure) 03/2024 - 01/2019
3	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 01/2023 - 01/2022

Drug/Important Bio-Agent (IBA)

66	CytokinesIBA 01/2024 - 07/2004
27	Antirheumatic Agents (DMARD)IBA 03/2024 - 06/2004
26	Interleukin-17 (Interleukin 17)IBA 03/2024 - 11/2007
24	secukinumabIBA 03/2024 - 02/2014
22	InterleukinsIBA 03/2024 - 08/2004
21	guselkumabIBA 03/2024 - 01/2020
18	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2019 - 05/2002
17	Monoclonal AntibodiesIBA 01/2022 - 11/2010
15	Janus Kinase InhibitorsIBA 01/2024 - 09/2013
14	Tumor Necrosis Factor InhibitorsIBA 03/2024 - 12/2002
14	AntigensIBA 02/2024 - 07/2004
14	Interleukin-23 (Interleukin 23)IBA 12/2023 - 04/2014
14	LipidsIBA 01/2022 - 05/2005
13	Methotrexate (Mexate)FDA LinkGeneric 03/2024 - 02/2007
13	Adalimumab (Humira)FDA Link 02/2024 - 07/2010
13	C-Reactive ProteinIBA 10/2022 - 08/2013
12	Biomarkers (Surrogate Marker)IBA 12/2023 - 03/2007
12	Interleukin-33IBA 01/2017 - 02/2008
11	tofacitinibIBA 12/2023 - 01/2014
11	golimumab FDA Link 01/2023 - 08/2012
11	CollagenIBA 01/2021 - 12/2002
11	Ustekinumab (CNTO 1275)FDA Link 11/2019 - 08/2013
11	Interleukin-18 (Interleukin 18)IBA 12/2018 - 01/2003
10	Abatacept (Orencia)FDA Link 02/2024 - 08/2010
10	Proteins (Proteins, Gene)FDA Link 02/2024 - 07/2004
10	Interleukin-12 (IL 12)IBA 01/2024 - 10/2004
10	ChemokinesIBA 01/2023 - 07/2008
10	AutoantibodiesIBA 01/2023 - 03/2010
9	bimekizumabIBA 03/2024 - 01/2019
8	upadacitinibIBA 01/2024 - 01/2020
8	tocilizumab (atlizumab)FDA Link 01/2023 - 04/2015
8	Interleukin-15 (Interleukin 15)IBA 01/2018 - 05/2002
7	AntibodiesIBA 02/2024 - 02/2008
7	Immunoglobulin G (IgG)IBA 01/2024 - 07/2004
7	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 12/2023 - 09/2013
7	Interleukin-6 (Interleukin 6)IBA 01/2023 - 08/2003
6	ametantrone (HAQ)IBA 03/2024 - 06/2014
6	CholesterolIBA 03/2024 - 02/2003
6	Interleukin-1 (Interleukin 1)IBA 01/2022 - 10/2004
6	LigandsIBA 01/2022 - 04/2009
6	Peptides (Polypeptides)IBA 04/2021 - 01/2009
5	Toll-Like Receptors (Toll-Like Receptor)IBA 12/2023 - 10/2011
5	Infliximab (Remicade)FDA Link 01/2023 - 09/2010
5	Etanercept (Enbrel)FDA Link 01/2023 - 01/2016
5	GlucocorticoidsIBA 01/2022 - 12/2018
5	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2020 - 02/2003
5	Collagen Type II (Type II Collagen)IBA 03/2016 - 01/2009
4	VaccinesIBA 05/2024 - 10/2021
4	Janus KinasesIBA 02/2023 - 01/2020
4	Anti-Citrullinated Protein AntibodiesIBA 01/2023 - 10/2013
4	Rituximab (Mabthera)FDA Link 01/2023 - 07/2016
4	baricitinibIBA 01/2023 - 12/2018
4	Sulfasalazine (Azulfidine)FDA LinkGeneric 01/2023 - 02/2007
4	OvalbuminIBA 01/2022 - 07/2004
4	AlarminsIBA 01/2019 - 05/2013
4	mavrilimumabIBA 01/2018 - 09/2013
4	Liver X ReceptorsIBA 06/2017 - 09/2009
4	MicroRNAs (MicroRNA)IBA 06/2017 - 03/2012
4	Brain Natriuretic Peptide (Natrecor)FDA Link 11/2016 - 07/2010
4	Lipoproteins (Lipoprotein)IBA 10/2016 - 09/2013
3	Interleukin-23 Subunit p19IBA 03/2024 - 01/2020
3	Rheumatoid FactorIBA 02/2024 - 01/2009
3	Adrenal Cortex Hormones (Corticosteroids)IBA 02/2024 - 03/2021
3	sarilumabIBA 12/2023 - 01/2020
3	omega-Chloroacetophenone (Mace)IBA 11/2023 - 01/2019

Therapy/Procedure

66	Therapeutics 05/2024 - 06/2004
7	Biological Therapy 10/2021 - 10/2006
3	Immunomodulation 02/2024 - 01/2020
3	Precision Medicine 12/2023 - 09/2019