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Juha Klefström Selected Research

Ligands

9/2010GATA4 protects granulosa cell tumors from TRAIL-induced apoptosis.

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Juha Klefström Research Topics

Disease

26Neoplasms (Cancer)
04/2024 - 07/2008
12Breast Neoplasms (Breast Cancer)
04/2024 - 07/2008
2Squamous Cell Carcinoma of Head and Neck
01/2024 - 03/2021
2Triple Negative Breast Neoplasms
11/2022 - 01/2022
2Carcinogenesis
01/2021 - 01/2018
2Neoplasm Metastasis (Metastasis)
01/2018 - 05/2015
1Acquired Immunodeficiency Syndrome (AIDS)
09/2023
1Circulating Neoplastic Cells
09/2023
1Mitochondrial Diseases (Mitochondrial Disease)
01/2023
1Hematologic Neoplasms (Hematological Malignancy)
01/2019
1Ovarian Neoplasms (Ovarian Cancer)
01/2018
1Neuroblastoma
11/2013
1B-Cell Lymphoma (Lymphoma, B Cell)
05/2013
1Peutz-Jeghers Syndrome (Polyposis, Hamartomatous Intestinal)
01/2013
1Prostatic Neoplasms (Prostate Cancer)
11/2009
1Infections
11/2009

Drug/Important Bio-Agent (IBA)

9Proteins (Proteins, Gene)FDA Link
10/2023 - 11/2009
6hepsinIBA
10/2023 - 01/2018
5Peptide Hydrolases (Proteases)FDA Link
11/2021 - 04/2017
3CytokinesIBA
04/2024 - 09/2010
3Serine Proteases (Serine Protease)IBA
10/2023 - 04/2017
3Phenobarbital (Luminal)FDA Link
11/2021 - 05/2015
3Phosphotransferases (Kinase)IBA
01/2019 - 02/2012
2Transcription Factors (Transcription Factor)IBA
01/2023 - 01/2018
2Estrogen ReceptorsIBA
11/2021 - 01/2016
2CollagenIBA
03/2021 - 01/2021
1Electron Transport Complex I (NADH-CoQ Reductase)IBA
04/2024
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2024
1ErbB Receptors (EGF Receptor)IBA
10/2023
1Neutralizing AntibodiesIBA
10/2023
1GelsIBA
09/2023
1FibrinIBA
09/2023
1NucleotidesIBA
01/2023
1Glutamine (L-Glutamine)FDA Link
01/2023
1Monoclonal AntibodiesIBA
01/2022
1Immune Checkpoint InhibitorsIBA
01/2022
1Trastuzumab (Herceptin)FDA Link
01/2022
1sortilinIBA
01/2022
1tyrosine receptor (receptor, tyrosine)IBA
01/2022
1Protein Kinases (Protein Kinase)IBA
01/2022
1InterferonsIBA
01/2022
1p38 Mitogen-Activated Protein KinasesIBA
11/2021
1Transforming Growth Factor beta (TGF-beta)IBA
11/2021
1Fibronectins (Fibronectin)IBA
11/2021
1Anoctamin-1IBA
03/2021
1ras ProteinsIBA
01/2021
1UbiquitinIBA
01/2020
1Ligases (Synthetase)IBA
01/2020
1venetoclaxIBA
01/2019
1Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA
01/2019
1Metformin (Glucophage)FDA LinkGeneric
01/2019
1navitoclaxIBA
01/2019
1matriptaseIBA
01/2019
1HGF activatorIBA
01/2019
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2018
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
01/2018
1Tretinoin (Retinoic Acid)FDA LinkGeneric
05/2015
1Serine (L-Serine)FDA Link
11/2013
1Protein Phosphatase 2 (Protein Phosphatase 2A)IBA
11/2013
1Phosphoprotein Phosphatases (Phosphatases, Protein)IBA
11/2013
1Tumor Suppressor Protein p53IBA
05/2013
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
01/2013
1GATA4 Transcription FactorIBA
09/2010
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2010
1LigandsIBA
09/2010
1Hormones (Hormone)IBA
11/2009
1Small Interfering RNA (siRNA)IBA
07/2008
1Ribosomal Protein S6 Kinases (S6 Kinase)IBA
07/2008
170-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA
07/2008

Therapy/Procedure

6Therapeutics
01/2022 - 11/2009
2Immunotherapy
11/2022 - 01/2022
1Drug Therapy (Chemotherapy)
04/2024