Efficacy of oral clorsulon in the treatment of Fasciola hepatica infections in calves.

Abstract

Twenty calves at each of 2 Arkansas locations were inoculated with infective Fasciola hepatica metacercariae. After 56 days, the calves at each site were randomly assigned by weight to 2 treatment groups of 10 calves/group; vehicle control or clorsulon at the rate of 7 mg/kg of body weight. All treatments were given orally as a suspension. Calves were killed 6 weeks after treatment and F hepatica counts were performed for all animals. At the 2 sites, mean levels of efficacy were 96% and 91%. Adverse reactions to clorsulon or the vehicle were not observed in the calves.

• Authors: T A Yazwinski, R L Kilgore, B L Presson, M L Williams, R K Fulton, L Pote, T E Greenway
• Journal: American journal of veterinary research (Am J Vet Res) Vol. 46 Issue 1 Pg. 163-4 (Jan 1985) ISSN: 0002-9645 [Print] United States
• PMID: 3970422 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antiplatyhelmintic Agents
• Sulfanilamides
• clorsulon

Topics

• Animals
• Antiplatyhelmintic Agents (therapeutic use)
• Cattle
• Cattle Diseases (drug therapy, parasitology)
• Fascioliasis (drug therapy, parasitology, veterinary)
• Liver (parasitology)
• Sulfanilamides (therapeutic use)