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Immunotherapy of guinea pig line 10 hepatoma with nonliving BCG cells in aqueous medium.

Abstract
Killed BCG cells suspended in 1.5% carboxymethylcellulose cured guinea pigs with established line 10 tumors in a high percentage of cases. The bacterial preparation of BCG in carboxymethylcellulose displayed a stronger tumor regressive activity and the process of healing was accelerated when endotoxin from a rough (Re) strain of Salmonella typhimurium was added to the BCG bacilli.
AuthorsA Bekierkunst, M B Goren
JournalInfection and immunity (Infect Immun) Vol. 24 Issue 3 Pg. 817-20 (Jun 1979) ISSN: 0019-9567 [Print] United States
PMID381203 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • BCG Vaccine
  • Bacterial Toxins
  • Endotoxins
  • Carboxymethylcellulose Sodium
Topics
  • Animals
  • BCG Vaccine (therapeutic use)
  • Bacterial Toxins (therapeutic use)
  • Carboxymethylcellulose Sodium (therapeutic use)
  • Endotoxins (therapeutic use)
  • Guinea Pigs
  • Liver Neoplasms, Experimental (therapy)
  • Salmonella typhimurium

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