Abstract | BACKGROUND: METHODS: RESULTS: LIMITATIONS: The limitations of this review include the relatively few articles included (n = 13) and small sample sizes (less than thirty subjects) in the majority of articles. CONCLUSION:
Vaccine response in adults with a mental disorder remains inconclusive. Notwithstanding the heterogeneity and relatively small number of studies, available evidence does suggest attenuated immune response across disparate vaccinations. Future research is required to confirm vaccine efficacy in persons with mental disorders, especially regarding immune responses to COVID-19 vaccination.
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Authors | Karren Xiao, Emily S Gillissie, Leanna M W Lui, Felicia Ceban, Kayla M Teopiz, Hartej Gill, Bing Cao, Roger Ho, Joshua D Rosenblat, Roger S McIntyre |
Journal | Journal of affective disorders
(J Affect Disord)
Vol. 304
Pg. 66-77
(05 01 2022)
ISSN: 1573-2517 [Electronic] Netherlands |
PMID | 35167926
(Publication Type: Journal Article, Review, Systematic Review)
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Copyright | Copyright © 2022 Elsevier B.V. All rights reserved. |
Chemical References |
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Topics |
- Adult
- COVID-19
(prevention & control)
- COVID-19 Vaccines
- Depressive Disorder, Major
- Humans
- Immunity
- Pandemics
- Stress Disorders, Post-Traumatic
- Vaccination
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