Comparison of clinical practice guidelines on radiation dermatitis: a narrative review.

Abstract

PURPOSE:

Radiation dermatitis (RD) is a common side effect of radiation therapy (RT). While many different treatment strategies are currently used to address RD, there is a lack of consensus and RD prophylaxis and management guidelines have remained largely unchanged over the last 10 years. This review aims to formulate unambiguous supportive care interventions by comparing RD clinical practice guidelines published between 2010 and 2021 by several organizations: Multinational Association for Supportive Care in Cancer (MASCC), British Columbia Cancer Agency (BCCA), Cancer Care Manitoba (CCMB), Oncology Nursing Society (ONS), Society and College of Radiographers (SCoR), and International Society of Nurses in Cancer Care (ISNCC).

METHODS:

Areas of agreement and discordance were assessed among the MASCC, BCCA, CCMB, ONS, SCoR, and ISNCC guidelines.

RESULTS:

Treatment recommendations across guidelines for acute RD and chronic RT-induced skin toxicities have been summarized. The strongest agreement among the guidelines exists for the use of topical corticosteroids, silver sulfadiazine, washing, and deodorant. All guidelines recommend the use of topical corticosteroids, and washing with water and soap is consistently supported. There is minimal consensus on an optimal dressing or barrier film for RD prophylaxis or management. MASCC weakly recommends prophylactic use of silver sulfadiazine to reduce RD, while BCCA, CCMB, and SCoR recommend its use upon signs of infection. MASCC and CCMB recommend the use of a long-pulsed dye laser to manage telangiectasia, a late effect of RT.

CONCLUSIONS:

Given the extent of discordance among guideline recommendations, further research is recommended to establish optimal treatments for RD prophylaxis and management.

• Authors: Samuel Finkelstein, Lauren Kanee, Tara Behroozian, Julie Ryan Wolf, Corina van den Hurk, Edward Chow, Pierluigi Bonomo
• Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (Support Care Cancer) Vol. 30 Issue 6 Pg. 4663-4674 (Jun 2022) ISSN: 1433-7339 [Electronic] Germany
• PMID: 35067732 (Publication Type: Journal Article, Review)
• Copyright: © 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Chemical References

• Adrenal Cortex Hormones
• Dermatologic Agents
• Silver Sulfadiazine

Topics

• Adrenal Cortex Hormones (therapeutic use)
• Dermatologic Agents
• Humans
• Neoplasms (therapy)
• Practice Guidelines as Topic
• Radiodermatitis (etiology, prevention & control)
• Silver Sulfadiazine (therapeutic use)