Abstract | BACKGROUND: OBJECTIVE: Our aim was to search and assess the scientific literature for information on trigger factors related to nutrition and physical activity in PPP. METHODS: We searched Ovid Medline and Embase database for scientific papers published between January 1, 1990, to January 31, 2020. RESULTS: We did not identify published observation or intervention studies evaluating effect of lifestyle changes on attacks. Current knowledge is based on case-reports, expert opinions, and retrospective case studies with inadequate methods for description of nutrition and physical activity. In HypoPP, high carbohydrate and salt intake, over-eating, alcohol, dehydration, hard physical activity, and rest after exercise are frequently reported triggers. Regarding HyperPP, fasting, intake of potassium, alcohol, cold foods or beverages, physical activity, and rest after exercise are frequently reported triggers. No nutrition related triggers are reported regarding ATS, exercise can however induce ventricular arrhythmias. CONCLUSIONS: Our results support that dietary intake and physical activity may play a role in causing paralytic attacks in PPP, although the current scientific evidence is weak. To provide good evidence-based patient care, several lifestyle aspects need to be further assessed and described.
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Authors | Natasha Lervaag Welland, Helge Hæstad, Hanne Ludt Fossmo, Kaja Giltvedt, Kristin Ørstavik, Marianne Nordstrøm |
Journal | Journal of neuromuscular diseases
(J Neuromuscul Dis)
Vol. 8
Issue 4
Pg. 457-468
( 2021)
ISSN: 2214-3602 [Electronic] Netherlands |
PMID | 33646174
(Publication Type: Journal Article, Review)
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Topics |
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Andersen Syndrome
(physiopathology)
- Diet
- Exercise
- Female
- Humans
- Male
- Middle Aged
- Paralyses, Familial Periodic
(physiopathology)
- Paralysis
(etiology)
- Young Adult
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