Abstract | INTRODUCTION: To investigate the effect of an exercise prescription and a 1-year supervised exercise intervention, and the modifying effect of the family history of type 2 diabetes (FH), on long-term cardiometabolic health. RESEARCH DESIGN AND METHODS: For this prospective randomized trial, we recruited non-diabetic participants with poor fitness (n=1072, 30-70 years). Participants were randomly assigned with stratification for FH either in the exercise prescription group (PG, n=144) or the supervised exercise group (EG, n=146) group and compared with a matched control group from the same population study (CON, n=782). The PG and EG received exercise prescriptions. In addition, the EG attended supervised exercise sessions two times a week for 60 min for 12 months. Cardiometabolic risk factors were measured at baseline, 1 year, 5 years, and 6 years. The CON group received no intervention and was measured at baseline and 6 years. RESULTS: CONCLUSIONS: Low-cost physical activity programs have long-term beneficial effects on cardiometabolic health regardless of the FH of diabetes. Given the feasibility and low cost of these programs, they should be advocated to promote cardiometabolic health. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov identifier NCT02131701.
|
Authors | Niko S Wasenius, Bo A Isomaa, Bjarne Östman, Johan Söderström, Björn Forsén, Kaj Lahti, Liisa Hakaste, Johan G Eriksson, Leif Groop, Ola Hansson, Tiinamaija Tuomi |
Journal | BMJ open diabetes research & care
(BMJ Open Diabetes Res Care)
Vol. 8
Issue 2
(11 2020)
ISSN: 2052-4897 [Electronic] England |
PMID | 33219117
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
|
Copyright | © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. |
Topics |
- Cardiovascular Diseases
(prevention & control)
- Diabetes Mellitus, Type 2
(therapy)
- Exercise
- Exercise Therapy
- Humans
- Prospective Studies
|