Abstract | BACKGROUND: METHODS: We combined the closed head weight-drop method and the nitroglycerin chronic migraine model. To induce mild traumatic brain injury, a weight was dropped onto intact crania of mildly anesthetized mice, and mechanical responses to chronic-intermittent administration of nitroglycerin, a human migraine trigger, were determined at multiple time points post-injury. RESULTS: CONCLUSIONS:
|
Authors | Laura S Moye, Madeline L Novack, Alycia F Tipton, Harish Krishnan, Subhash C Pandey, Amynah Aa Pradhan |
Journal | Cephalalgia : an international journal of headache
(Cephalalgia)
Vol. 39
Issue 1
Pg. 77-90
(01 2019)
ISSN: 1468-2982 [Electronic] England |
PMID | 29771142
(Publication Type: Journal Article)
|
Chemical References |
|
Topics |
- Animals
- Brain Concussion
(complications)
- Disease Models, Animal
- Hyperalgesia
(metabolism)
- Male
- Mice
- Mice, Inbred C57BL
- Migraine Disorders
(etiology, metabolism)
- Post-Traumatic Headache
(etiology, metabolism)
- Receptors, Opioid, delta
(metabolism)
- Trigeminal Ganglion
(metabolism)
|