[Adrenal myelolipoma].

Abstract

This paper is a review of the literature about adrenal myelolipoma. It is a rare, benign, hormonally inactive tumor of the adrenal gland composed of mature fat tissue and hematopoietic tissue in varying amounts. Adrenal myelolipoma is usually small (< 4 cm), unilateral and causes no clinical disorders. The age range of the affected patients is 20-90 years; most are men in their fourth to sixth decade. This tumour is discovered during autopsy or USG, CT MRI of the abdomen usually by chance and because of that is included in the group of tumors called incidentaloma. Etiology of myelolipoma is unclear. It is usually hormonally inactive but there were several cases in which adrenal myelolipoma coexisted with various endocrine disorders such as Cushing's syndrome, Conn's syndrome, Addison's disease, hirsutism, hermaphroditism, inborn deficiencies of 17- and 21-hydroxylase. It is also more frequent in patients with obesity, hypertension and leading stressful life. Surgical treatment is called for when the diameter of tumor reaches more than 4 cm, tumour shows tendency to fast growth or causes clinical disorders. In cases of small lesions, that show no progression, it is advised to observe the tumor using imaging techniques.

• Authors: Grazyna Bednarek-Tupikowska, Krzysztof Tupikowski, Bernice F Akinpelumi
• Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego (Pol Merkur Lekarski) Vol. 18 Issue 103 Pg. 107-10 (Jan 2005) ISSN: 1426-9686 [Print] Poland
• Vernacular Title: Myelolipoma nadnerczy.
• PMID: 15859562 (Publication Type: English Abstract, Journal Article, Review)

Topics

• Adrenal Gland Neoplasms (diagnosis, surgery)
• Diagnosis, Differential
• Humans
• Myelolipoma (diagnosis, surgery)