High Fructose Corn Syrup

Syrup made from corn used widely in foods and beverages as a cheaper alternative sweetener to SUCROSE (common table sugar). It is generated by enzymatic processing of natural corn syrup to produce a liquid most widely composed of 42 or 55% FRUCTOSE, GLUCOSE, and various POLYSACCHARIDES.

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Networked: 174 relevant articles (1 outcomes, 23 trials/studies)

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Bio-Agent Context: Research Results

Experts

1.	Johnson, Richard J: 8 articles (01/2019 - 03/2006)
2.	Tucker, Katherine L: 6 articles (12/2020 - 10/2015)
3.	Lanaspa, Miguel A: 5 articles (01/2019 - 10/2013)
4.	Nakagawa, Takahiko: 5 articles (01/2019 - 03/2006)
5.	Havel, Peter J: 4 articles (04/2022 - 06/2013)
6.	Stanhope, Kimber L: 4 articles (04/2022 - 06/2013)
7.	Lowndes, Joshua: 4 articles (03/2014 - 12/2008)
8.	Rippe, James M: 4 articles (03/2014 - 12/2008)
9.	Goran, Michael I: 3 articles (04/2022 - 01/2013)
10.	Keim, Nancy L: 3 articles (04/2022 - 01/2018)

Related Diseases

1.	Inflammation (Inflammations) 01/01/2022 - "We showed that kefir feeding ameliorates lymphocyte infiltration on the high-fructose corn syrup (HFCS)-induced masseter muscle and gingival tissue inflammation in rats. " 10/31/2023 - "The present study showed that high-fructose corn syrup (HFCS) administration exacerbated intestinal inflammation and deteriorated barrier integrity. " 01/01/2022 - "The aim of the study was to evaluate whether high-fructose corn syrup (HFCS) intake (20% beverages) impacts antioxidative structures and inflammation in the gingival tissue and masseter muscle of rats. " 10/01/2019 - "High fructose corn syrup (HFCS) has been shown to cause cardiovascular toxicity via oxidative stress and inflammation. " 02/01/2016 - "The aim of this study was to evaluate the role of α-lipoic acid (α-LA) on oxidative damage and inflammation that occur in endothelium of aorta and heart while constant consumption of high-fructose corn syrup (HFCS). "
2.	Body Weight (Weight, Body) 06/01/2013 - "Many studies have shown that ingestion of high-fructose corn syrup (HFCS) may cause an increase in body weight and abdominal fat. " 06/01/1990 - "Effect of drinking soda sweetened with aspartame or high-fructose corn syrup on food intake and body weight." 11/01/2010 - "High-fructose corn syrup causes characteristics of obesity in rats: increased body weight, body fat and triglyceride levels." 01/01/2018 - "Our previous study demonstrated that when compared with aspartame (Asp), 2 wk of high-fructose corn syrup (HFCS)-sweetened beverages provided at 25% of daily energy requirement was associated with increased body weight, postprandial (pp) triglycerides (TG), and fasting and pp CVD risk factors in young adults. " 01/01/2019 - "The effect of high fructose corn syrup on the plasma insulin and leptin concentration, body weight gain and fat accumulation in rat."
3.	Obesity 03/02/2022 - "Effects of high fructose corn syrup on intestinal microbiota structure and obesity in mice." 01/01/2021 - "High fructose corn syrup (HFCS) is widely used in beverages and is often included in food products with moderate or high fat content that have been linked to many serious health issues including diabetes and obesity. " 01/28/2019 - "Scientific evidence has identified that the excessive consumption of products made from high-fructose corn syrup is a trigger for obesity, whose prevalence increased in recent years. " 04/05/2017 - "Ingestion of high-fructose corn syrup (HFCS) is associated with the risk of both diabetes and obesity. " 01/01/2017 - "The contribution of high fructose corn syrup (HFCS) to metabolic disorder and obesity, independent of high fat, energy-rich diets, is controversial. "
4.	Non-alcoholic Fatty Liver Disease 04/01/2015 - "High fructose corn syrup (HFCS)-containing beverages were associated with metabolic abnormalities, and contributed to the development of NAFLD in human trials. " 01/01/2021 - "Non-alcoholic fatty liver disease (NAFLD) is an increasingly prevalent condition that has been linked to high-fructose corn syrup consumption with induction of hepatic de novo lipogenesis (DNL) as the suggested central mechanism. " 01/01/2023 - "Integrated omics analysis for characterization of the contribution of high fructose corn syrup to non-alcoholic fatty liver disease in obesity." 11/01/2008 - "The aims of this study were to determine whether combining features of a western lifestyle in mice with trans fats in a high-fat diet, high-fructose corn syrup in the water, and interventions designed to promote sedentary behavior would cause the hepatic histopathological and metabolic abnormalities that characterize nonalcoholic steatohepatitis (NASH). " 11/01/2021 - "However, the effect of high-fructose corn syrup (HFCS) compared with sucrose in pediatric NAFLD has not been investigated. "
5.	Fatty Liver 02/22/2019 - "The chronic ingestion of excessive amounts of high-fructose corn syrup is associated with an increased prevalence of fatty liver. " 01/01/2017 - "Effect of Restriction of Foods with High Fructose Corn Syrup Content on Metabolic Indices and Fatty Liver in Obese Children." 09/01/2015 - "The increased consumption of high-fructose corn syrup (HFCS) may contribute to the worldwide epidemic of fatty liver. " 01/01/2021 - "The rapid increase in obesity, diabetes and fatty liver disease in children over the past 20 years has been linked to increased consumption of high fructose corn syrup (HFCS), making it essential to determine the short- and long-term effects of HFCS during this vulnerable developmental window. " 01/01/2022 - "This study was designed to reveal the effect of probiotics and omega-3 fatty acids in a fatty liver model in rats induced by high-fructose corn syrup (HFCS). "

Related Drugs and Biologics

1.	Sucrose (Saccharose)
2.	Sugars
3.	Fructose
4.	Glucose (Dextrose)
5.	Aspartame (NutraSweet)
6.	Lipids
7.	Fats
8.	Triglycerides (Triacylglycerol)
9.	Omega-3 Fatty Acids (Omega 3 Fatty Acids)
10.	Drinking Water

Related Therapies and Procedures

1.	Carbohydrate-Restricted Diet (Low Carbohydrate Diet)
2.	Intravenous Injections
3.	Reducing Diet
4.	Canes (Cane)