Paleolithic Diet

A nutritional plan based on the presumed diet of pre-agricultural human ancestors. It consists mainly of MEAT, EGGS, NUTS, roots and fresh VEGETABLES and FRUITS, and excludes GRAIN, LEGUMES, DAIRY PRODUCTS, and refined DIETARY SUGARS.

Also Known As:

Diet, Paleolithic; Diet, Caveman; Diet, Hunter-Gatherer; Diet, Paleo; Diet, Stone Age; Caveman Diet; Caveman Diets; Diet, Hunter Gatherer; Diets, Caveman; Diets, Hunter-Gatherer; Diets, Paleo; Diets, Stone Age; Hunter-Gatherer Diet; Hunter-Gatherer Diets; Paleo Diet; Paleo Diets; Stone Age Diet; Stone Age Diets

Networked: 66 relevant articles (9 outcomes, 21 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Ryberg, Mats: 8 articles (09/2021 - 01/2015)
2.	Olsson, Tommy: 7 articles (09/2021 - 01/2015)
3.	Otten, Julia: 7 articles (09/2021 - 01/2017)
4.	Stomby, Andreas: 7 articles (09/2021 - 01/2015)
5.	Wahls, Terry L: 7 articles (01/2021 - 01/2015)
6.	Waling, Maria: 5 articles (09/2021 - 01/2017)
7.	Bisht, Babita: 5 articles (01/2021 - 01/2015)
8.	Jönsson, Tommy: 5 articles (07/2013 - 12/2005)
9.	Lindeberg, Staffan: 5 articles (07/2013 - 12/2005)
10.	Svensson, Michael: 4 articles (09/2021 - 01/2017)

Related Diseases

1.	Type 2 Diabetes Mellitus (MODY) 07/29/2013 - "We found marked improvement of glycemic control and several cardiovascular risk factors in patients with type 2 diabetes given advice to follow a Paleolithic diet, as compared to a diabetes diet. " 07/16/2009 - "Over a 3-month study period, a Paleolithic diet improved glycemic control and several cardiovascular risk factors compared to a Diabetes diet in patients with type 2 diabetes." 03/17/2021 - "This study is a secondary analysis of a randomized controlled trial using Paleolithic diet and exercise in individuals with type 2 diabetes. " 01/01/2018 - "A heterogeneous response of liver and skeletal muscle fat to the combination of a Paleolithic diet and exercise in obese individuals with type 2 diabetes: a randomised controlled trial." 01/01/2019 - "Exercise Training Adds Cardiometabolic Benefits of a Paleolithic Diet in Type 2 Diabetes Mellitus."
2.	Insulin Resistance 01/01/2019 - "Combating insulin resistance with the paleo diet." 01/01/2018 - "The aim of the study was to investigate ectopic fat deposition and insulin sensitivity, in a parallel single-blinded randomised controlled trial, comparing Paleolithic diet alone with the combination of Paleolithic diet and exercise in individuals with type 2 diabetes. " 01/01/2017 - "Benefits of a Paleolithic diet with and without supervised exercise on fat mass, insulin sensitivity, and glycemic control: a randomized controlled trial in individuals with type 2 diabetes." 09/01/2015 - "On the contrary, a simplified way of eating healthily by excluding highly-processed foods, is presumed to be the Paleolithic diet (a diet based on vegetables, fruits, nuts, roots, meat, organ meats) which improves insulin resistance, ameliorates dyslipidemia, reduces hypertension and may reduce the risk of age-related diseases. " 08/01/2015 - "Also, on the Paleo diet, the most insulin-resistant subjects had a significant improvement in insulin sensitivity (r = 0.40, P = 0.02), but no such effect was seen in the most insulin-resistant subjects on the ADA diet (r = 0.39, P = 0.3). "
3.	Weight Loss (Weight Reduction) 01/01/2020 - "Intermittent fasting (IF) and Paleolithic (Paleo) diets produce weight loss in controlled trials, but minimal evidence exists regarding long-term efficacy under free-living conditions without intense dietetic support. " 11/01/2021 - "The paleo diet is popular among the general population due to promoted weight loss and disease prevention benefits. " 01/01/2021 - "The Paleolithic diet, characterized by an emphasis on hunter-gatherer type foods accompanied by an exclusion of grains, dairy products, and highly processed food items, is often promoted for weight loss and a reduction in cardiometabolic disease risk factors. " 06/01/2019 - "Results In the Paleolithic diet group, mean weight loss compared to baseline was 11% at 6 months and 10% at 24 months. " 01/01/2019 - "The analysis showed a positive association of adopting the Paleolithic diet in relation to weight loss. "
4.	Ketosis 01/01/2021 - "Participants consuming the MCT-based ketogenic diet achieved nutritional ketosis; however, it was not associated with significant clinical improvement in this study whereas the modified Paleolithic diet was associated with significant clinical improvements. "
5.	Overweight 11/01/2021 - "Single-Arm 8-Week Ad Libitum Self-Prepared Paleo Diet Reduces Cardiometabolic Disease Risk Factors in Overweight Adults." 05/01/2015 - "Forty-nine overweight/obese postmenopausal women were randomized to a paleolithic diet or a diet according to NNR for 24 months. " 01/01/2015 - "20 overweight postmenopausal women were randomized to either a modified paleolithic diet or a standard diet adhering to the Nordic Nutrition Recommendations for 6 months. " 01/01/2020 - "This exploratory, observational analysis examined adherence, dietary intake, weight loss, and metabolic outcomes in overweight adults who could choose to follow Mediterranean, IF, or Paleo diets, and standard exercise or high-intensity interval training (HIIT) programs, as part of a 12-mo randomized controlled trial investigating how different monitoring strategies influenced weight loss (control, daily self-weighing, hunger training, diet/exercise app, brief support). " 01/01/2019 - "Methods and Results Twenty-two overweight and obese subjects with type 2 diabetes mellitus were randomized to either a Paleolithic diet and standard-care exercise recommendations ( PD ) or to a Paleolithic diet plus supervised exercise training 3 hours per week ( PD - EX ). "

Related Drugs and Biologics

1.	Triglycerides (Triacylglycerol)
2.	Insulin (Novolin)
3.	Glucose (Dextrose)
4.	Carbohydrates
5.	C-Reactive Protein
6.	Glucagon-Like Peptide 1 (GLP 1)
7.	Metformin (Glucophage)
8.	HDL Cholesterol
9.	Glycated Hemoglobin (Glycosylated Hemoglobin)
10.	Glucagon (Glukagon)

Related Therapies and Procedures

1.	Glycemic Control
2.	Ketogenic Diet
3.	Mediterranean Diet
4.	Vegan Diet (Diet, Vegan)
5.	Gluten-Free Diet