Non-Nutritive Sweeteners

Chemical additives, such as aspartame, saccharin, and sucralose, that give a sweet taste to foods without contributing significant calories or promoting tooth decay. They are generally much sweeter than sucrose.

Also Known As:

Artificial Sweeteners, Non-Nutritive; High-Intensity Sweeteners; Artificial Sweeteners, Non Nutritive; High Intensity Sweeteners; Non Nutritive Sweeteners; Non-Nutritive Artificial Sweeteners; Sweeteners, High-Intensity; Sweeteners, Non-Nutritive

Networked: 71 relevant articles (1 outcomes, 15 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Swithers, Susan E: 8 articles (06/2016 - 08/2009)
2.	Davidson, Terry L: 3 articles (04/2013 - 04/2010)
3.	Davidson, T L: 3 articles (07/2012 - 08/2009)
4.	Martin, Ashley A: 3 articles (07/2011 - 04/2010)
5.	Bertoluci, Marcello Casaccia: 2 articles (01/2020 - 01/2017)
6.	Foletto, Kelly Carraro: 2 articles (01/2020 - 01/2017)
7.	Pinto, Denise Entrudo: 2 articles (01/2020 - 01/2017)
8.	Aasbrenn, Martin: 2 articles (01/2018 - 01/2017)
9.	Farup, Per G: 2 articles (01/2018 - 01/2017)
10.	Sample, Camille H: 2 articles (04/2013 - 01/2013)

Related Diseases

1.	Weight Loss (Weight Reduction) 01/01/2017 - "Acute and medium-term intervention studies suggest that non-nutritive sweeteners (NNS) are beneficial for weight loss, however there is limited human data on the long-term effects of consuming NNS on weight loss, maintenance, and appetite. " 06/01/2014 - "Can non-nutritive sweeteners enhance outcomes of weight loss interventions?" 11/01/2013 - "Amidst this rise of weight loss diets, there has been a surge of individual products advertised as assuring quick weight loss; one such product group is non-nutritive sweeteners (NNS). " 10/10/2023 - "Non-nutritive Sweeteners: Weight Loss or Weight Gain?" 02/01/2016 - "To evaluate the effects of water versus beverages sweetened with non-nutritive sweeteners (NNS) on body weight in subjects enrolled in a year-long behavioral weight loss treatment program. "
2.	Body Weight (Weight, Body) 04/28/2021 - "The aim of this study was to evaluate the effects of non-nutritive sweeteners (NNS) consumption on energy intake, body weight and postprandial glycemia in healthy and with altered glycemic response rats. " 11/27/2023 - "Non-nutritive sweeteners and body weight management: another brick in the wall of evidence." 04/28/2021 - "Effects of Non-Nutritive Sweeteners on Energy Intake, Body Weight and Postprandial Glycemia in Healthy and with Altered Glycemic Response Rats." 01/01/2018 - "Consuming the high-intensity sweeteners did not affect body weight, self-reported dietary consumption, or self-reported physical activity. " 10/01/2016 - "The claim that non-nutritive sweeteners accelerate body weight gain by disrupting sweet-calorie associations was tested in two experiments using rats. "
3.	Obesity 01/01/2023 - "Stratified estimates were significant only in adolescents, participants with obesity at baseline, consumers of a mixture of non-nutritive sweeteners, longer trials, and trials not found to have potential conflicts of interest. " 12/01/2023 - "Overconsumption of non-nutritive sweeteners is associated with obesity, whereas the underlying mechanisms remain controversial. " 12/01/2022 - "The relationship between the consumption of maternal non-nutritive sweeteners (NNS) during pregnancy and the risk of obesity in offspring remains inconsistent. " 10/01/2020 - "Consumption of non-nutritive sweeteners (NNS) is becoming increasingly more frequent, particularly in the context of obesity prevention policies. " 01/01/2020 - "Consumption of non-nutritive sweeteners (NNS) has been consistently associated with obesity and cardiometabolic disease in epidemiologic studies. "
4.	Weight Gain 12/01/2010 - "Previous studies show that high-intensity sweeteners can stimulate weight gain in rats. " 04/01/2013 - "These results suggest that the most negative consequences of consuming high-intensity sweeteners may occur in those most likely to use them for weight control, females consuming a "Westernized" diet and already prone to excess weight gain." 07/01/2011 - "To review the recent work on potential mechanisms underlying a paradoxical positive association between the consumption of non-nutritive sweeteners (NNS) and weight gain. " 10/10/2023 - "Non-nutritive Sweeteners: Weight Loss or Weight Gain?" 06/01/2021 - "Non-nutritive sweeteners (NNSs) are commonly used to prevent weight gain and development of metabolic diseases associated with consumption of high-energy diets. "
5.	Type 2 Diabetes Mellitus (MODY) 12/13/2021 - "The data overall has yet to show a strong and clear link between consumption of non-nutritive sweeteners and the development of type 2 diabetes. " 12/13/2021 - "Consumption of Non-nutritive Sweeteners and Risk for Type 2 Diabetes: What Do We Know, and Not?" 09/01/2019 - "In our paper, we aim to investigate whether non-nutritive sweeteners consumption prevents or causes type 2 diabetes. " 09/01/2019 - "Non-nutritive sweeteners and type 2 diabetes: Should we ring the bell?" 06/30/2020 - "Non-nutritive Sweeteners and Their Associations with Obesity and Type 2 Diabetes."

Related Drugs and Biologics

1.	Sugars
2.	Glucose (Dextrose)
3.	Aspartame (NutraSweet)
4.	Saccharin
5.	Sweetening Agents (Sweeteners)
6.	Cyclamates (Cyclamate)
7.	Food Additives (Food Additive)
8.	acetosulfame (acesulfame K)
9.	Nutritive Sweeteners
10.	Nitrites

Related Therapies and Procedures

1.	Glycemic Control
2.	Nutrition Therapy (Medical Nutrition Therapy)
3.	Therapeutics
4.	Reducing Diet