Time-to-Treatment

The interval of time between onset of symptoms, or suspicion of disease and initiation of therapy; being a combination of wait times for consultative, diagnostic, and treatment services.

Also Known As:

Networked: 1576 relevant articles (109 outcomes, 241 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Marson, Anthony G: 17 articles (01/2022 - 03/2007)
2.	Tudur Smith, Catrin: 11 articles (01/2022 - 11/2007)
3.	Molina, Carlos A: 10 articles (09/2014 - 09/2004)
4.	Saver, Jeffrey L: 9 articles (01/2020 - 11/2011)
5.	De Luca, Giuseppe: 9 articles (07/2014 - 03/2004)
6.	Nevitt, Sarah J: 8 articles (01/2022 - 01/2018)
7.	Goyal, Mayank: 8 articles (12/2021 - 09/2015)
8.	Roberts, Ian: 8 articles (01/2021 - 03/2011)
9.	Ribo, Marc: 8 articles (09/2014 - 09/2004)
10.	Schonewille, Wouter J: 7 articles (01/2022 - 08/2009)

Related Diseases

1.	Stroke (Strokes) 11/01/2019 - "Time to treatment in acute stroke was dramatically improved with a simple intervention. " 01/01/2021 - "As technology and computational resources have advanced, several novel point-of-care medical devices show promise in facilitating rapid stroke diagnosis, with the potential for improving time to treatment and informing prehospital stroke triage." 06/01/2019 - "In logistic regression analysis (adjusted for age, National Institutes of Health Stroke Scale, and time-to-treatment ≤6/>6 hours), revascularization was associated with good outcome in patients with favorable BATMAN score (odds ratio, 15.8; 95% CI, 1.4-175; P=0.02) or PC-CS (odds ratio, 9.4; 95% CI, 1.4-64; P=0.02). " 01/01/2019 - "Conclusions- Interventions in the workflow of endovascular stroke treatment lead to a significant reduction in time to treatment and results in an increased likelihood of favorable outcome. " 11/01/2017 - "The introduction of new organizational concepts in the rescue chain and in acute inpatient services can significantly reduce time to treatment and patients can receive specific therapeutic options that have been shown to improve acute stroke prognosis. "
2.	Neoplasms (Cancer) 09/19/2014 - "An elevated pretreatment lymphocyte-to-monocyte ratio (LMR) is reportedly associated with improved overall survival (OS) and a longer time to treatment recurrence (TTR) in some types of cancers. " 01/01/2023 - "Time to treatment for a new diagnosis of cancer is directly associated with improved outcomes with little no describing the ED utilization prior to the diagnosis of cancer. " 12/01/2023 - "We evaluated whether Medicaid expansion (ME) was associated with improved 2-year survival and time to treatment initiation (TTI) among patients with gastrointestinal (GI) cancer. " 12/01/2019 - "Use of combinations of cancer drugs, sequential therapy, adaptive therapy and topical ablation of drug-resistant malignant lumps may help to prolong the time to treatment failure. " 01/01/2016 - "Reduction in time to treatment is associated with improved outcome independent of tumor stage, underlying liver function, and treatment."
3.	Breast Neoplasms (Breast Cancer) 05/01/2020 - "Compared with conventional chemotherapy, PB improved the overall response rate and time to treatment failure in patients with HER2- advanced breast cancer and improved overall survival in some patient subgroups." 01/01/2023 - "Shorter Time to Treatment Is Associated With Improved Survival in Rural Patients With Breast Cancer Despite Other Adverse Socioeconomic Factors." 07/01/2017 - "Implementation of a multidisciplinary patient navigation program reduced time to treatment and improved compliance with adjuvant therapy for breast cancer in an underserved minority community." 01/01/2016 - "An additional RT facility in NQ has led to an increase in patients treated with RT for prostate and breast cancer and, on average, less travel distance and time to treatment, suggesting improvement in access to RT in NQ." 01/01/2023 - "This study examined differences in time to treatment initiation (TTI), a potential surrogate for access, and predictors of overall survival (OS) between rural and nonrural patients with breast cancer. "
4.	Seizures (Absence Seizure) 04/01/2012 - "Outcomes were time to treatment failure overall, because of inadequate seizure control, and because of adverse events, and time to 12 months of remission from seizures. " 06/01/2007 - "It is safe and effective in terminating seizures and reduces the time to treatment and the need for emergency department visits when used in the school setting, and can be administered by medical and delegated to trained nonmedical personnel. " 11/05/2007 - "Primary outcomes were time to treatment failure and time to 12 month remission from seizures. " 10/01/2007 - "Time to treatment failure (withdrawal of the randomised drug for reasons of unacceptable adverse events or inadequate seizure control or a combination of the two) and time to achieve a 12-month remission of seizures. " 01/01/2023 - "The secondary outcomes included cumulative incidences of the following: (1) time to treatment failure due to uncontrolled seizures; (2) time to treatment failure due to adverse effects; and (3) time to recurrent seizures. "
5.	Infarction (Infarctions) 01/01/2020 - "Our finding that time to treatment and successful reperfusion were not associated with improved outcome is likely due to including patients with established infarcts. " 07/01/2001 - "Clinical factors predictive of global and regional ventricular function as well as improvement in function between 90 minutes and 5 to 7 days included time to treatment, early infarct-related artery flow grade, and body mass index. " 09/08/1993 - "A secondary analysis of time to treatment and outcome showed that treatment initiated within 70 minutes of symptom onset was associated with better outcome (composite score, P = .009; mortality, 1.2% vs 8.7%, P = .04; infarct size, 4.9% vs 11.2%, P < .001; and ejection fraction, 53% vs 49%, P = .03) than later treatment. " 06/01/2020 - "This study shows that transferred patients experience a greater overall system delay, compared to patients who present directly for PCI, significantly increasing their time to treatment and therefore infarct times. " 12/01/1995 - "Further studies need to be addressed in regards to the region of viable brain in the peri-infarct area, in reducing the time to treatment."

Related Drugs and Biologics

1.	Afatinib
2.	Gefitinib (Iressa)
3.	Phenytoin (Dilantin)
4.	Carbamazepine (Tegretol)
5.	ErbB Receptors (EGF Receptor)
6.	Tamoxifen
7.	Tissue Plasminogen Activator (Alteplase)
8.	Phenobarbital (Luminal)
9.	Doxorubicin (Adriamycin)
10.	Prednisone (Sone)

Related Therapies and Procedures

1.	Therapeutics
2.	Drug Therapy (Chemotherapy)
3.	Thrombolytic Therapy
4.	Percutaneous Coronary Intervention
5.	Induction Chemotherapy