Ascorbate Peroxidases

Peroxidases that utilize ASCORBIC ACID as an electron donor to reduce HYDROGEN PEROXIDE to WATER. The reaction results in the production of monodehydroascorbic acid and DEHYDROASCORBIC ACID.

Also Known As:

Networked: 120 relevant articles (4 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Jiang, Mingyi: 4 articles (07/2009 - 09/2002)
2.	Subramaniam, Sreeramanan: 2 articles (03/2022 - 01/2015)
3.	Ali, Sajid: 2 articles (07/2021 - 01/2021)
4.	Anwar, Raheel: 2 articles (07/2021 - 01/2021)
5.	Chauhan, Puneet Singh: 2 articles (05/2020 - 01/2016)
6.	Gupta, Swati: 2 articles (05/2020 - 01/2016)
7.	Mishra, Shashank Kumar: 2 articles (05/2020 - 01/2016)
8.	Xu, Fangxu: 2 articles (08/2019 - 04/2015)
9.	Cao, Xiaochuang: 2 articles (03/2019 - 01/2017)
10.	Jin, Qianyu: 2 articles (03/2019 - 01/2017)

Related Diseases

1.	Weight Loss (Weight Reduction) 04/20/2023 - "Postharvest treatment with melatonin 0.5 mmol L-1 improved firmness and reduced weight loss and non-commercial fruit percentage while increasing respiration rate, lipophilic antioxidant activity, and ascorbate peroxidase enzyme activity. " 07/15/2021 - "The combination of CA along with AA + OA reduced weight loss and maintained higher anthocyanins, total phenolics, membrane integrity, ascorbate peroxidase, catalase, glutathione reductase and superoxide dismutase activities compared with control. " 04/21/2021 - "Total soluble solids (TSS), weight loss, titratable acidity (TA), antioxidant activity (DPPH assay), total phenolic (TPC), flavonoid and anthocyanin contents (TFC), and enzymes activity (peroxidase and ascorbate peroxidase) were evaluated during the refrigerated period (5 °C with relative humidity of 85-90% for 20 days). " 06/15/2011 - "Mushroom weight loss, firmness, colour, percent open caps, total phenolics, ascorbic acid and H2O2 contents, superoxide anion (O2(-)) production rate and activities of polyphenol oxidase (PPO), superoxide dismutase (SOD), catalase (CAT), and ascorbate peroxidase (APX) were measured. " 01/01/2021 - "ALV coated fruits and vegetables showed reduced weight loss, superoxide ion ( O2-∙ ), hydrogen peroxide (H2 O2 ), ion leakage, and soluble solids content and exhibited higher acidity, anthocyanins, ascorbic acid, catalase (CAT), superoxide dismutase (SOD), and ascorbate peroxidase (APX) activities. "
2.	Infections 09/01/2000 - "Increased ascorbate peroxidase (APX) activity was detected upon infection, especially in the compatible interaction. " 10/01/2020 - "For the first time, two groups have published AP-MS studies using the same tool, the ascorbate peroxidase proximity labeling system (APEX2), which overcomes past experimental limitations because membrane protein interactions are labeled in vivo in the context of infection. " 07/01/2023 - "During plant-pathogen interaction, when the invader spreads systemically throughout the plant, the main role of ascorbate peroxidase (APX; EC 1.11.1.11) activity in one moderately resistant variety (Olimpija) and catalase (CAT; EC 1.11.1.6) activity in another moderately resistant variety (Alka) is to protect the plant against oxidative damage in the early stages of infection. " 01/01/2020 - "Regarding the antioxidant system, ascorbate peroxidase has an important role in H2O2 resistance and may be responsible for the high infection rates previously described for A. " 10/01/2023 - "As a result, epidermal cell density, leaf area, petiole length, and chlorophyll content were reduced while the density of stomata and trichome and phenolic content and the activity of ascorbate peroxidase (APX) and glutathione reductase (GR) were increased in response to Fv infection in Nb. "
3.	Dehydration (Water Stress) 01/01/2016 - "Transformation of plum plants with a cytosolic ascorbate peroxidase transgene leads to enhanced water stress tolerance." 01/01/2020 - "peroxidase and ascorbate peroxidase) was not sufficient to overcome the H2O2 accumulation triggered by water stress. " 05/01/2011 - "Xanthi) plants overexpressing cytosolic Cu/Zn-superoxide dismutase (cytsod) (EC 1.15.1.1) or ascorbate peroxidase (cytapx) (EC 1.11.1.1) alone, or in combination, were produced and tested for tolerance against mild water stress. " 03/01/2007 - "During the period of intensified water stress, the peak value of ascorbate peroxidase (AsA-POD) activity was 0.435 mg x g(-1) FM, and up to 0.490 mg x g(-1) FM when treated with exogenous betaine. " 08/01/2002 - "During water stress, with a few exceptions, ascorbate peroxidase and catalase activities increased moderately in leaves but decreased in nodules. "
4.	Disease Resistance 03/07/2023 - "Furthermore, both VvBKI1 and VvAPX1 transgenic Arabidopsis showed an elevated ascorbate peroxidase activity and enhanced disease resistance. " 01/01/2015 - "The known proteins were categorised into 5 classes, among these proteins, some pathogenesis-related (PR) proteins, such as beta-1,3-glucanase, ascorbate peroxidase (APX), glutathione peroxidase (GPX) and mal d1, were identified in susceptible and resistant hosts and were associated with disease resistance of the apple host. " 02/01/2013 - "The enhanced accumulation of signal transduction proteins such as a C2H2 zinc finger protein, stress/defence/detoxification proteins including LEA-related COR protein, disease resistance protein, Cu/Zn superoxide dismutase, and two ascorbate peroxidases may play crucial roles in the mechanisms of response to spring freeze stress in wheat plants." 02/07/2014 - "Among of these proteins, there are some PR proteins, for example class III endo-chitinase, beta-1,3-glucanase and thaumatine-like protein, and some antioxidant related proteins including aldo/keto reductase AKR, ascorbate peroxidase and phi class glutathione S-transferase protein that were associated with disease resistance. " 09/15/2011 - "They are l-ascorbate peroxidase, putative short-chain dehydrogenase/reductase, Glycolipid transfer protein, elongation factor, Os04g0652700, carbonic anhydrase, Os08g0374000, chitinase, and putative disease resistance response protein. "
5.	Necrosis 11/01/2007 - "Arabidopsis thaliana deficient in two chloroplast ascorbate peroxidases shows accelerated light-induced necrosis when levels of cellular ascorbate are low." 08/01/1997 - "Symptom appearance after TMV inoculation was preceded by a slight, transient decline of ascorbate peroxidase, GR, GST, and SOD activities in the inoculated lower leaves, but after the onset of necrosis these activities and the glutathione level substantially increased. " 03/01/2001 - "Activities of guaiacol peroxidase, ascorbate peroxidase and glutathione reductase were enhanced, while catalase exhibited a decrease in activity, with the appearance of visible necrosis in both the hybrids. " 03/01/2013 - "Our results showed that SiAR significantly caused leaf necrosis, inhibited photosynthesis, induced superoxide radical and hydrogen peroxide generation, aggravated membrane lipid peroxidation, changed antioxidant enzyme activities, modified related protein expressions such as Cu/Zn superoxide dismutase (SOD), l-ascorbate peroxidase (APX, EC 1. 11. " 12/01/2013 - "After 15 and 30 days of in vitro culture, shoot and root growth, chlorosis and necrosis extension, chlorophylls, carotenoids, proline, arginine, cysteine and total sugars content, as well as guaiacol peroxidase (G-POD, EC 1.11.1.7) and ascorbate peroxidase (APX, EC 1.11.1.11) activities were determined. "

Related Drugs and Biologics

1.	Superoxide Dismutase
2.	Catalase
3.	Enzymes
4.	Antioxidants
5.	Glutathione Reductase (Glutathione-Disulfide Reductase)
6.	Peroxidase (Myeloperoxidase)
7.	Glutathione (Reduced Glutathione)
8.	Ascorbic Acid (Vitamin C)
9.	guaiacol peroxidase
10.	Phenylalanine Ammonia-Lyase

Related Therapies and Procedures

1.	Rewarming
2.	Aftercare (After-Treatment)