HLA-B14 Antigen

A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*14 allele family.

Also Known As:

HLA B14; HLA B14 Antigen; HLA Class I Histocompatibility Antigen, B-14 alpha Chain; HLA-B14; Antigen, HLA B14; Antigen, HLA-B14; B14 Antigen, HLA; HLA Class I Histocompatibility Antigen, B 14 alpha Chain

Networked: 38 relevant articles (3 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Al-Shamahy, Hassan A: 1 article (05/2015)
2.	Masood, Haitham A A: 1 article (05/2015)
3.	Nassar, Mogahid Y: 1 article (05/2015)
4.	Bjarnadottir, Kristjana: 1 article (09/2013)
5.	Gislason, Thorarinn: 1 article (09/2013)
6.	Gudbjornsson, Bjorn: 1 article (09/2013)
7.	Gudmundsson, Sveinn: 1 article (09/2013)
8.	Haraldsdottir, Sigridur Olina: 1 article (09/2013)
9.	Jonsson, Thorbjorn: 1 article (09/2013)
10.	Petursdottir, Dyrleif: 1 article (09/2013)

Related Diseases

1.	Lymphoma (Lymphomas) 05/27/2003 - "There was also no evidence of a relation of lymphoma risk with the presence or absence of any particular HLA antigen, although significant protective effects of HLA-B14 and -B57 were found when analyses were conducted without adjustment for multiple testing. "
2.	Coronary Disease (Coronary Heart Disease) 10/01/1984 - "The findings helped to draw a conclusion as to the presence of associative links between a number of the studied antigens (A (II), MN, HLA-B7, HLA-B14, HLA-B15, HLA-CW4) and the risk of the development of, at least, some forms of coronary heart disease."
3.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/01/2006 - "HLA B14 and A24 were increased and showed statistically significant correlation in squamous cell carcinoma. "
4.	Congenital adrenal hyperplasia due to 21 hydroxylase deficiency 10/01/1987 - "In the present series, the enzymatic defect was found to have a considerably lower prevalence than in a previous study of smaller size (15% vs 66%); however, considering the low frequency of the gene coding for the defect in the general population (0.015-0.057), the present results confirm an increased risk for non-classic 21-hydroxylase deficiency in HLA-B14 positive individuals. " 05/01/1986 - "Previous studies have shown that the late-onset and cryptic forms of 21-hydroxylase deficiency are highly associated with the HLA supratype HLA-B14,C4A2,C4B1/2,DR1. " 02/01/2004 - "All patients with the V281L mutation presented HLA-B14 (100%) and six of them presented DR1 (60%), confirming that LOCAH is linked to the histocompatibility complex. " 06/01/1990 - "Also in keeping with earlier reports, we continue to note the absence of association between nonclassic 21-hydroxylase deficiency occurring among Yugoslavs and HLA-B14; DR1." 01/01/1989 - "A CYP21B gene from a HLA-B14;DR1 homozygous patient with nonclassic 21-hydroxylase deficiency was cloned and analyzed. "
5.	Gout 11/01/1994 - "The genetic study showed an increased frequency of HLA-B14 in patients with primary gout compared with controls. " 11/01/1994 - "There was an increased frequency of HLA-B14 in patients with primary gout but the clinical significance of this is uncertain." 01/01/1978 - "An increased "relative risk" of the disease was established in patients carrying antigen HLA-B14, but the correlation is not sufficient for using HLA typing as a diagnostic tool in the gout. "

Related Drugs and Biologics

1.	Antigens
2.	HLA-B15 Antigen
3.	HLA-C*04 antigen
4.	HLA-B5 antigen
5.	Genetic Markers (Genetic Marker)
6.	Blood Group Antigens (Blood Groups)
7.	HLA-A*30 antigen
8.	HLA-B8 Antigen (HLA B8 Antigen)
9.	HLA-A3 Antigen (HLA A3 Antigen)
10.	HLA-A11 Antigen