Adjuvant Chemoradiotherapy

Combined chemotherapy and radiotherapy given to augment some other form of treatment such as surgery. It is commonly used in the therapy of cancer.

Also Known As:

Chemoradiotherapy, Adjuvant; Adjuvant Radiochemotherapy; Radiochemotherapy, Adjuvant; Adjuvant Chemoradiotherapies; Adjuvant Radiochemotherapies; Chemoradiotherapies, Adjuvant; Radiochemotherapies, Adjuvant

Networked: 772 relevant articles (57 outcomes, 157 trials/studies)

Relationship Network

Therapy Context: Research Results

Therapeutics: 1158551

Experts

1.	Kim, Kyubo: 25 articles (12/2021 - 11/2005)
2.	Chie, Eui Kyu: 24 articles (10/2021 - 11/2005)
3.	Jang, Jin-Young: 22 articles (02/2022 - 02/2009)
4.	Oh, Do-Youn: 20 articles (10/2021 - 02/2009)
5.	Kim, Sun Whe: 18 articles (10/2018 - 11/2005)
6.	Bang, Yung-Jue: 17 articles (09/2017 - 11/2005)
7.	Ha, Sung W: 16 articles (09/2017 - 11/2005)
8.	Kim, Byoung Hyuck: 12 articles (12/2021 - 04/2015)
9.	Im, Seock-Ah: 12 articles (04/2017 - 02/2009)
10.	Kim, Tae-You: 12 articles (04/2017 - 02/2009)

Related Diseases

1.	Neoplasms (Cancer) 10/01/2009 - "Results from the Mayo Clinic suggest improved outcomes after the administration of adjuvant radiochemotherapy after a complete resection of invasive pancreatic malignancies." 01/01/2018 - "While grades II and III present more aggressive course and might require adjuvant radiochemotherapy, grade I tumors have a good outcome after gross total resection. " 10/15/2012 - "Patients with node-positive disease had improved survival with adjuvant chemoradiotherapy, especially when we grouped patients with N1 and N2 tumors and a higher N-ratio. " 07/01/2011 - "Adjuvant chemoradiotherapy was associated with improved overall and cancer-specific survival for patients with advanced disease. " 06/01/2019 - "The 5-year OS and DFS were improved by adjuvant chemoradiotherapy in the subgroups of males, tumor located at the middle of thoracic esophagus, moderate differentiation, number of resected lymph nodes <15. "
2.	Adenocarcinoma 01/01/2012 - "In the pivotal Intergroup-0116 Phase III trial by Macdonald et all, adjuvant chemoradiotherapy improved both disease-free and overall survival in curatively resected patients with mainly gastric adenocarcinoma. " 11/01/2004 - "Improved disease free and overall survivals were seen in curatively resected patients with gastric and gastroesophageal adenocarcinoma treated with the Intergroup 0116 (INT 0116) protocol of postoperative adjuvant chemoradiotherapy compared to surgery alone. " 02/01/2008 - "Adjuvant chemoradiotherapy improved survival in patients with resected gastric adenocarcinoma in the Southwest Oncology Group/Intergroup 0116 trial. " 08/15/2022 - "For Siewert type II/III adenocarcinoma of gastroesophageal junction (AGE), the efficacy of adjuvant chemoradiotherapy (CRT) after D2/R0 resection remains uncertain. " 01/01/2018 - "Over the past decade, several multimodality adjunctive treatments have improved survival for patients with operable gastroesophageal adenocarcinoma who are undergoing surgical resection; these include peri-operative chemotherapy, neoadjuvant chemoradiotherapy, adjuvant chemotherapy and adjuvant chemoradiotherapy. "
3.	Stomach Neoplasms (Stomach Cancer) 01/01/2020 - "In patients with locoregionally advanced gastric cancer treated with curative intent with surgery and adjuvant radiochemotherapy, the overall 5-year survival reported from local clinical practice is similar to that reported in randomised series and supports its use as an effective treatment for this type of patients in our country." 03/01/2010 - "Adjuvant chemoradiotherapy does not represent the standard of care in patients with resected high-risk gastric cancer; however, results from phase 2 and randomized trials suggest improvement in overall survival. " 01/01/2022 - "Although adjuvant therapy has been shown to be beneficial in gastric cancer, the use of adjuvant chemoradiotherapy remains controversial. " 04/01/2010 - "The association of combined adjuvant chemoRT with improved survival in an overall analysis of Stage IB through Stage IV (M0) resected gastric cancer is consistent with clinical trial results and suggests that, in an elderly population, adjuvant chemoradiotherapy is effective. " 12/01/2023 - "Perioperative chemotherapy, adjuvant chemotherapy, and adjuvant chemoradiotherapy (CRT) have all been demonstrated to be effective in the treatment of gastric cancer. "
4.	Carcinoma (Carcinomatosis) 11/01/2012 - "Although no consensus exists regarding ideal therapy for advanced base-of-tongue carcinoma, combined strategies with the use of surgery and adjuvant chemoradiotherapy (CRT) seem to offer the best possibility for a positive outcome." 09/01/2011 - "The efficacy of adjuvant radiochemotherapy (RCT) in patients with advanced stage head and neck carcinoma has been proven in prospective randomized trials. " 01/01/2018 - "Adjuvant Chemoradiotherapy is Associated with Improved Survival for Patients with Resected Gallbladder Carcinoma: A Systematic Review and Meta-analysis." 03/01/2013 - "This study aimed to perform a meta-analysis of eligible published clinical trials to compare CRT with surgery without adjuvant chemoradiotherapy (non-CRT) for resectable esophageal carcinoma. " 11/16/2012 - "Nevertheless, the results of the recently published ARTIST trial and the Chinese data by Zhu and coworkers, indicate a superiority of adjuvant radiochemotherapy as compared to adjuvant chemotherapy in terms of disease free survival in Asian patients with advanced gastric carcinoma. "
5.	Rectal Neoplasms (Rectal Cancer) 07/01/2017 - "Neo-adjuvant chemoradiotherapy (NACRT) combined with total mesorectal excision (TME) surgery is the main treatment for locally advanced middle-low rectal cancer, and NACRT significantly improves the local control rate of rectal cancer. " 06/01/2013 - "KRAS mutation does not predict the efficacy of neo-adjuvant chemoradiotherapy in rectal cancer: a systematic review and meta-analysis." 10/01/2010 - "Due to improvements in operative techniques, such as the establishment of total mesorectal excision (TME) and the combination of surgery and (neo-) adjuvant radiochemotherapy, the incidence of locally recurrent rectal cancer could be improved from nearly 50% to less then 10%. " 01/01/2023 - "We searched for randomized controlled trials (RCTs) in people with stage I rectal cancer comparing any modern LE techniques to any RR techniques with or without the use of neo/adjuvant chemoradiotherapy (CRT). " 04/30/2021 - "Short-term safety of adjuvant chemoradiotherapy after local resection for patients with high-risk submucosal invasive rectal cancer: a single-arm, multicenter phase II trial."

Related Drugs and Biologics

1.	Fluorouracil (Carac)
2.	Leucovorin (Folinic Acid)
3.	Oxaliplatin (Eloxatin)
4.	fisetin
5.	Temozolomide (Temodar)
6.	Gemcitabine
7.	Proteins (Proteins, Gene)
8.	Cyclin-Dependent Kinase Inhibitor p16
9.	Uracil
10.	Tamoxifen

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Adjuvant Chemotherapy
3.	Radiotherapy
4.	Neoadjuvant Therapy
5.	Chemoradiotherapy