Methyclothiazide

A thiazide diuretic with properties similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p825)

Also Known As:

2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-, 1,1-dioxide

Networked: 30 relevant articles (0 outcomes, 2 trials/studies)

Drug Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazides: 1584
    - Benzothiadiazines: 3
      - Methyclothiazide: 30
        Lometazid
  - Sulfones: 534
    - Sulfonamides: 2809
      - Benzothiadiazines: 3
        Methyclothiazide: 30
        Lometazid
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzothiadiazines: 3
      - Methyclothiazide: 30
        Lometazid

Experts

1.	Chan, Cynthia Y: 1 article (11/2012)
2.	Ng, Tien M H: 1 article (11/2012)
3.	Peterson, Evan J: 1 article (11/2012)
4.	Club des jeunes hypertensiologues: 1 article (07/2006)
5.	Denolle, T: 1 article (07/2006)
6.	Dourmap, C: 1 article (07/2006)
7.	Fauvel, J P: 1 article (07/2006)
8.	Fourcade, J: 1 article (07/2006)
9.	Girerd, X: 1 article (07/2006)
10.	Hanon, O: 1 article (07/2006)

Related Diseases

1.	Hypertension (High Blood Pressure) 06/01/1978 - "Methyclothiazide would seem to be a suitable choice for the treatment of mild hypertension in general practice." 06/01/1978 - "Methyclothiazide in hypertension. " 05/01/1978 - "[Treatment of uncomplicated arterial hypertension with methyclothiazide]." 11/01/1968 - "Parglyline hydrochloride and methyclothiazide combined in the treatment of hypertension in diabetic patients." 06/01/1978 - "In view of the statistically significant falls in blood pressure achieved at the end of two weeks only, it would seem that methyclothiazide is an effective antihypertensive agent, at least in the new cases of mild hypertension treated in this trial. "
2.	Essential Hypertension 12/01/1977 - "Influence of dosage and duration of therapy on the rate of response to methyclothiazide in essential hypertension." 12/01/1977 - "One hundred twenty patients with essential hypertension were studied to determine whether patients who had not responded to the usual dose of a thiazide (methyclothiazide, 5 mg daily during a six-week drug trial) would respond to a higher dose (10 mg daily). " 01/01/1968 - "Clinical and laboratory observations on the use of a combination of methyclothiazide and deserpidine in treatment of essential hypertension." 08/01/1966 - "Pargyline hydrochloride combined with methyclothiazide in the treatment of essential hypertension." 11/01/1963 - "A COMPARATIVE CLINICAL STUDY OF METHYCLOTHIAZIDE AND PARGYLINE IN PATIENTS WITH ESSENTIAL HYPERTENSION."
3.	Edema (Dropsy) 02/01/1966 - "Methyclothiazide in excessive weight gain and edema of pregnancy." 03/01/1963 - "A comparative study of diuretic agents, methyclothiazide and dihydrochlorothiazide, in patients with chronic edema."
4.	Renal Insufficiency (Renal Failure) 11/01/2012 - "Key words included thiazide*, hydrochlorothiazide, chlorothiazide, chlorthalidone, indapamide, metolazone, methyclothiazide, bendroflumethiazide, hemodialysis, dialysis, kidney failure, renal failure, renal insufficiency, hypertension, vasodilation, vascular, and diuretics. "
5.	Weight Gain 02/01/1966 - "Methyclothiazide in excessive weight gain and edema of pregnancy."

Related Drugs and Biologics

1.	Antihypertensive Agents (Antihypertensives)
2.	Thiazides
3.	Pargyline (Pargyline Hydrochloride)
4.	deserpidine
5.	Hydrochlorothiazide (Esidrix)
6.	Diuretics
7.	Indapamide
8.	Chlorothiazide
9.	Drinking Water
10.	Sodium Chloride Symporter Inhibitors (Diuretics, Thiazide)

Related Therapies and Procedures

1.	Therapeutics
2.	Renal Dialysis (Hemodialysis)
3.	Duration of Therapy