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Amoxicillin (Wymox)

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A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.

Also Known As:

Wymox; Amoxicilline; Amoxil; Trimox; Actimoxi; Amoxicillin monopotassium salt; Amoxicillin monosodium salt; Amoxicillin trihydrate; Amoxicillin, (R*)-isomer; Amoxycillin; BRL-2333; Clamoxyl; Clamoxyl G.A.; Clamoxyl parenteral; Clariana Brand of Amoxicillin; Penamox; Pfizer Brand of Amoxicillin Sodium Salt; Polymox; SmithKline Beecham Brand of Amoxicillin Sodium Salt; Amoxicillin Clariana Brand; BRL 2333; BRL2333; G.A., Clamoxyl; parenteral, Clamoxyl; trihydrate, Amoxicillin; Hydroxyampicillin; 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((amino(4-hydroxyphenyl)acetyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta(S*)))-

Networked: 3351 relevant articles (501 outcomes, 586 trials/studies) for this Drug, Comments

Relationship Network

Drug Context: Research Results

Experts

1.	Brook, Itzhak: 9 articles (05/2009 - 04/2002)
2.	Gober, Alan E: 6 articles (05/2009 - 04/2002)
3.	Feres, Magda: 5 articles (12/2012 - 10/2008)
4.	Torres, M J: 5 articles (11/2011 - 02/2002)
5.	Blanca, M: 5 articles (11/2011 - 02/2002)
6.	Aguilar, Lorenzo: 5 articles (01/2011 - 11/2003)
7.	Soriano, Francisco: 5 articles (06/2010 - 08/2002)
8.	Jacobs, Michael R: 5 articles (12/2007 - 10/2002)
9.	Socransky, Sigmund S: 4 articles (12/2012 - 01/2012)
10.	Figueiredo, Luciene Cristina: 4 articles (12/2012 - 10/2008)

Related Diseases

1.	Infection 06/01/2006 - "Amoxicillin-based therapies are highly effective for the treatment of Helicobacter pylori infections, but the efficacy may decrease as the incidence of amoxicillin resistance is increasing. " 08/01/2005 - "In conclusion, the efficacy of these two dosage regimens of amoxycillin was not significantly different in treatment of acute Ap-infection in pigs." 07/01/2001 - "The PA infection was treated successfully with amoxicillin." 05/01/1984 - "Similarly, those with infections caused by amoxicillin-susceptible organisms were cured at a significantly higher rate than those with infections caused by resistant organisms (85 versus 50%; P less than 0.001). " 10/01/2002 - "Microgranulated amoxicillin is suitable for in-feed administration to pigs and, because of its higher oral bioavailability compared with the powdered compound, it may be more effective for the treatment of susceptible infections." Order ALL the reference details at left...
2.	Otitis Media 01/01/2011 - "RESULTS: Watchful waiting, followed by amoxicillin treatment, if necessary, is the best first-line treatment for acute otitis media in children aged six months or older." 12/01/1989 - "Amoxicillin is the standard of therapy for infants and children with acute otitis media, because it is safe and effective for most of the causative bacterial pathogens. " 08/01/2004 - "Developing community-specific recommendations for first-line treatment of acute otitis media: is high-dose amoxicillin necessary?" 05/01/2003 - "Bacteriologic and clinical efficacy of high dose amoxicillin for therapy of acute otitis media in children." 12/01/1986 - "Because reduction in division of the amoxicillin dose caused no significant difference in the efficacy of antibiotic treatment of acute otitis media in infants and children, we think that this simplified scheme of therapy can routinely be used in clinical practice and thus improve compliance to antibiotic administration." Order ALL the reference details at left...
3.	Pneumonia (Pneumonitis) 12/01/2007 - "Oral amoxicillin is effective for most children admitted to hospital with pneumonia (all but those with the most severe disease who were excluded from this study). " 09/01/2011 - "On review after 48 h, if improved, the child may be sent home on oral amoxicillin for 5 more days; if not, it is treated as very severe pneumonia. " 04/01/2010 - "The findings demonstrate that oral amoxicillin is a cost-effective treatment for the majority of children admitted to hospital with pneumonia." 08/15/2004 - "Oral amoxicillin, if equally effective for treating severe pneumonia, would address challenges associated with providing parenteral therapy, including risk of transmission of bloodborne pathogens from contaminated needles, exposure to nosocomial pathogens during hospitalization, inadequate access to health care facilities, and cost. " 09/14/2002 - "Clinical efficacy of 3 days versus 5 days of oral amoxicillin for treatment of childhood pneumonia: a multicentre double-blind trial." Order ALL the reference details at left...
4.	Respiratory Tract Infections (Respiratory Tract Infection) 04/01/2002 - "To compare the efficacy of amoxicillin vs placebo in patients with an acute upper respiratory tract infection and purulent rhinorrhea. " 01/01/1981 - "Prospective clinical trial on the efficacy of amoxycillin administered twice or four times daily in children with respiratory tract infections." 11/01/1986 - "The present study compares the clinical efficacy and side-effects of amoxycillin in two groups of children at the age of six years or less randomly assigned to amoxycillin therapy 40 mg/kg/day either two or three times daily for the clinical diagnosis of acute respiratory tract infections. " 09/01/2010 - "Median plasma and tissue amoxicillin concentrations were respectively 4.7 microg/ml (IQR 2.1-8.0; min-max 0.4-14.3) and 1.1 microg/g (IQR 0.4-2.1; min-max 0.4-12.9), considerably below the selected target MIC of pathogens involved in the upper respiratory tract infections (S. " 08/01/2002 - "We thus consider that amoxycillin remains a useful initial choice for the treatment of paediatric respiratory infections in Japan." Order ALL the reference details at left...
5.	Urinary Tract Infections (Urinary Tract Infection) 12/01/1982 - "We conclude that a single 3 g dose of amoxicillin, with follow-up urine culture, provides safe and effective management for acute uncomplicated urinary tract infections in nonpregnant women." 02/23/1978 - "Efficacy of single-dose and conventional amoxicillin therapy in urinary-tract infection localized by the antibody-coated bacteria technic." 02/01/2006 - "The data collected were compared with those of a previous trial performed in the same setting and documenting the effectiveness and advantages associated with the use of amoxicillin against community-acquired uncomplicated urinary tract infections (UTI). " 06/01/1983 - "A comparative trial of amoxycillin 3g bd and conventional amoxycillin therapy in the treatment of urinary tract infection in a general practice population." 02/01/1983 - "[Clinical study on long acting amoxicillin in urinary tract infection]." Order ALL the reference details at left...

Related Drugs and Biologics

1.	Clavulanic Acid (Potassium Clavulanate)
2.	Clarithromycin (Biaxin)
3.	Omeprazole (Esomeprazole)
4.	Metronidazole (Metric)
5.	Penicillins (Penicillin)
6.	Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)
7.	Cefaclor (Ceclor)
8.	Azithromycin (Zithromax)
9.	Erythromycin (Erycette)
10.	Trimethoprim-Sulfamethoxazole Combination (Co-Trimoxazole)

Related Therapies and Procedures

1.	Aftercare (After-Treatment)
2.	Injections
3.	Drug Therapy (Chemotherapy)
4.	Retreatment
5.	Debridement

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