Dust Mite Allergy

Allergic rhinitis due to HOUSE DUST MITE ALLERGENS (e.g., Der p 1 of HOUSE DUST MITES) that is triggered by the immune system.

Also Known As:

Allergy, Dermatophagoides farinae; Allergy, Dermatophagoides pteronyssinus; Allergy, Dust Mite; Dermatophagoides farinae Allergies; Dermatophagoides pteronyssinus Allergies; Dust Mite Hypersensitivities; Hypersensitivity, Dust Mite; Dermatophagoides farinae Allergy; Dermatophagoides pteronyssinus Allergy; Dust Mite Hypersensitivity; House Dust Mite Allergy; House Dust Mite Hypersensitivity

Networked: 183 relevant articles (15 outcomes, 28 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Allergic Rhinitis
2.	Asthma (Bronchial Asthma)
3.	Seasonal Allergic Rhinitis (Hay Fever)
4.	Hypersensitivity (Allergy)
5.	Rhinitis

Experts

1.	Vrtala, Susanne: 5 articles (01/2017 - 01/2008)
2.	Valenta, Rudolf: 4 articles (01/2016 - 01/2008)
3.	Thomas, Wayne R: 4 articles (10/2015 - 01/2008)
4.	Jacquet, A: 4 articles (01/2010 - 07/2002)
5.	Zhou, Ying: 3 articles (10/2018 - 01/2016)
6.	Jacquet, Alain: 3 articles (09/2013 - 06/2005)
7.	Valent, Peter: 3 articles (08/2012 - 01/2008)
8.	Brzoza, Zenon: 3 articles (12/2009 - 05/2007)
9.	Kasperska-Zajac, Alicja: 3 articles (12/2009 - 05/2007)
10.	Kramer, Matthias F: 2 articles (01/2022 - 01/2016)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Dust Mite Allergy:

1.	AllergensIBA 09/09/2022 - "Targeting an Initiator Allergen Provides Durable and Expansive Protection against House Dust Mite Allergy." 10/01/1996 - "Previous study by the current authors has shown that treating homes with D'Allergen, an acaricidal agent, can reduce bronchial hyper-reactivity in asthmatic children with house dust mite allergy. " 11/01/2017 - "Comparison of two different assays and the predictive value of allergen components in house dust mite allergy." 01/01/2016 - "House dust mite hypersensitivity affects millions of people worldwide, and although many allergens produced by house dust mite species have been identified, some of the less potent allergens remain to be studied. " 09/01/2015 - "Total symptom scores (TSSs) were recorded by 21 participants with house dust mite allergy (M+) in the natural setting and during repeated exposures of 3 hours per day to house dust mite allergen in an allergen challenge chamber (ACC). "
2.	benzyl benzoate (Ansar)FDA Link 04/01/1998 - "Clinical effects of benzyl benzoate in the prevention of house-dust-mite allergy. " 10/01/1994 - "Home mattresses of 24 asthmatic children with house dust mite allergy were sprayed with either benzyl-benzoate foam or placebo in a double blind fashion, 10 days before the children left the residential house for asthmatic children Istituto Pio XII (located in the Italian Alps in an environment free of mites) and went back to their own home for the Christmas and Easter holidays. " 01/01/1992 - "[Acarex test and acarosan effect in house dust mite allergy in 2 year follow-up]." 05/01/1994 - "The efficacy of acaricid benzyl-benzoate (Acarosan) has been followed in an open study for one year in patients with house dust mite allergy; the clinical signs and the mite allergen level have been considered. " 04/01/1998 - "The efficacy of the acaricide benzyl benzoate as an additive to a chemically and technically defined cleaning substance (Acarosan) was tested in a multicentric, prospective, randomized, controlled study on 118 outpatients with bronchial asthma due to house-dust-mite allergy. "
3.	AcaricidesIBA 12/01/1994 - "Effects of an acaricide on asthmatic children with house dust mite allergy." 07/01/1991 - "Effectiveness of an acaricide in management of house dust mite allergy." 04/01/1998 - "The efficacy of the acaricide benzyl benzoate as an additive to a chemically and technically defined cleaning substance (Acarosan) was tested in a multicentric, prospective, randomized, controlled study on 118 outpatients with bronchial asthma due to house-dust-mite allergy. " 05/01/1995 - "Efficacy of the acaricide: acardust for the prevention of asthma and rhinitis due to dust mite allergy, in children."
4.	Proteins (Proteins, Gene)FDA Link 10/01/2015 - "The allergenic load of house dust mite allergy is largely constituted by a few proteins with a hierarchical pattern of allergenicity. " 10/26/2016 - "We identify a protein secreted by hookworms, anti-inflammatory protein-2 (AIP-2), that suppressed airway inflammation in a mouse model of asthma, reduced expression of costimulatory markers on human dendritic cells (DCs), and suppressed proliferation ex vivo of T cells from human subjects with house dust mite allergy. " 07/01/2003 - "The presence of IgE directed to the 60-kd protein in sera from humans and dogs with dust mite allergy was measured by FcepsilonRIalpha-based ELISA. " 12/21/2007 - "A recombinant fragment of SP-D that is effective in diminishing allergic hypersensitivity in mouse models of dust mite allergy was more susceptible to degradation than the native full-length protein. " 01/01/2016 - "This initial cloning and characterization of the Der f 4 allergen serves as a foundation for future studies into the clinical importance and application of this protein for house dust mite allergy."
5.	TabletsIBA 11/01/2016 - "The more recent experimental data on MK-8237 sublingual tablets provided evidence that AIT, in the sublingual form, is effective in dust mite allergy. " 01/01/2014 - "Tolerability during double-blind randomized phase I trials with the house dust mite allergy immunotherapy tablet in adults and children." 01/01/2015 - "House dust mite allergy immunotherapy tablet." 01/01/2016 - "Immunotherapy tablet helps control asthma in people with house dust mite allergy."
6.	PowdersIBA 10/01/2007 - "The study aimed to investigate the efficacy of inert cellulose powder applied to the nose for the control of persistent allergic rhinitis in adults due to house dust mite allergy. " 10/01/2007 - "The inert cellulose powder can have significant effects in reducing some symptoms of persistent rhinitis due to house dust mite allergy."
7.	CelluloseIBA 10/01/2007 - "The study aimed to investigate the efficacy of inert cellulose powder applied to the nose for the control of persistent allergic rhinitis in adults due to house dust mite allergy. " 10/01/2007 - "The inert cellulose powder can have significant effects in reducing some symptoms of persistent rhinitis due to house dust mite allergy."
8.	allergovitIBA 01/01/1995 - "The aim of this study was to evaluate the efficacy, tolerance and immunogenity of allergenic extracts: Allergovit and Novo-Hellisen depot (produced by Allergopharma--Germany), used for sIT in pollinosis and house dust mite allergy. " 01/01/1995 - "It was shown that the allergenic extracts Allergovit and Novo-Helisen depot are effective in treatment of pollinosis and house dust mite allergy, and are well tolerated by the patients. "
9.	VaccinesIBA 01/11/2008 - "Generation of a transgenic rice seed-based edible vaccine against house dust mite allergy." 12/01/2017 - "Safety of a proteoliposome from Neisseria meningitides as adjuvant for a house dust mite allergy vaccine." 01/01/2014 - "Therefore, we sought to investigate how recombinant major dust mite allergen Der p2-expressing Lactococcus lactis as a mucosal vaccine induced the immune tolerance against house dust mite allergy in a mouse model. " 03/01/2009 - "plantarum producing Der p 1 represents a promising vaccine against house dust mite allergy." 06/01/2005 - "In conclusion, recombinant ProDer p 1 complexed with diC14-amidine could represent an efficient prophylactic vaccine against house dust mite allergy."
10.	DNA VaccinesIBA 09/01/2013 - "Is electroporation decisive for the efficacy of DNA vaccine against house dust mite allergy?" 03/01/2013 - "Optimization of a Der p 2-based prophylactic DNA vaccine against house dust mite allergy." 02/20/2006 - "Protective effect of the DNA vaccine encoding the major house dust mite allergens on allergic inflammation in the murine model of house dust mite allergy." 01/01/2010 - "A codon-optimized DNA vaccine encoding mature Der p 1 in a lipoplex formulation could represent a promising hypoallergenic vaccine candidate for safer immunotherapy against house dust mite allergy."

Therapies and Procedures

1.	Immunotherapy 01/01/2007 - "Recent meta-analyses show that sublingual allergen immunotherapy for grass pollen and house dust mite allergy is clinically effective and safer than injection immunotherapy. " 12/01/2021 - "Meta-analyses comparing the efficacy of sublingual immunotherapy (SLIT) and subcutaneous immunotherapy (SCIT) for house dust mite allergy are lacking. " 04/01/2023 - "New approaches to immunotherapy in house dust mite allergy." 04/01/2019 - "Association Between Component-Resolved Diagnosis of House Dust Mite Allergy and Efficacy and Safety of Specific Immunotherapy." 07/01/2018 - "Immunotherapy for house-dust mite allergy."
2.	Therapeutics 12/01/1995 - "Dust mite therapy is most efficacious in children with isolated dust mite allergy. " 05/10/1981 - "Clinical aspects of house dust mite allergy and specific therapy in sensitization against house dust mites]." 01/01/2020 - "Notably, the current asthma guidelines are now recommending sublingual immunotherapy as an add-on therapy for asthma in adults and adolescents with house dust mite allergy. " 05/01/2001 - "A total of 256 patients were admitted, all with dust mite allergy; if pharmacological therapy failed after 12 months, they were assigned to immunotherapy (95 patients), either by subcutaneous injection or by the intranasal or sublingual route, depending on the main clinical-prognostic features taken into consideration. " 01/01/2018 - "Results from recent clinical studies have implemented the evidence of effectiveness and safety of allergen immunotherapy for the treatment of allergic asthma, so that the current asthma guidelines now recommend sublingual immunotherapy as an add-on therapy for asthma in adults and adolescents with house dust mite allergy, allergic rhinitis, and exacerbations despite low-to-moderate dose ICS, with forced expiratory volume in 1 second more than 70% predicted. "
3.	Root Planing 12/01/2019 - "Effect of scaling and root planing on level of immunoglobulin E and immunoglobulin G4 in children with gingivitis and house-dust mite allergy: A pilot randomised controlled trial."
4.	Subcutaneous Injections 05/01/2001 - "A total of 256 patients were admitted, all with dust mite allergy; if pharmacological therapy failed after 12 months, they were assigned to immunotherapy (95 patients), either by subcutaneous injection or by the intranasal or sublingual route, depending on the main clinical-prognostic features taken into consideration. " 01/01/2023 - "A total of 50 allergic rhinoconjunctivitis children with dust mite allergy was randomly divided into ICLIT group and SCIT group, receiving three cervical intralymphatic injections of dust mite allergen or three years of subcutaneous injection, separately. "
5.	Intralymphatic Injections 01/01/2023 - "A total of 50 allergic rhinoconjunctivitis children with dust mite allergy was randomly divided into ICLIT group and SCIT group, receiving three cervical intralymphatic injections of dust mite allergen or three years of subcutaneous injection, separately. "