[Effect of a mite-killing agent on house dust and on symptoms of house dust allergy].

Abstract

UNLABELLED:

The efficacy of acaricid benzyl-benzoate (Acarosan) has been followed in an open study for one year in patients with house dust mite allergy; the clinical signs and the mite allergen level have been considered.

METHODS:

the furniture (beds, upholstered pieces, carpets) of 17 house dust mite allergic patients suffering from bronchial asthma and/or allergic rhinitis has been investigated. The mite content of the dust gained from the furniture has been determined with the help of the semiquantitative Acarex test. This test has been done before the mite elimination and 3, 6, 9 and 12 months after it. The registered clinical signs of the patients: symptoms, drug consumption, expiratory peak flow values have been measured twice a day.

RESULTS:

9/17 beds have become free from mites, 6/17 beds have had less mites than before, 1/17 no change, 1/17 augmentation of mite content. The proportion of days free from complaints has been 26.8% at the beginning of the trial and 47.1% after 12 months, the drug consumption has diminished meanwhile. At the beginning of the trial 6 children had pathologic lability index based on peak-flow measurements, they improved significantly. The information about the mite content of the furniture gives help for the elimination measures. The chemical mite elimination reduces the mite content of the flat and results in clinical improvement of house dust mite allergic patients.

• Authors: G Mezei, E Cserháti, A Pusztai
• Journal: Orvosi hetilap (Orv Hetil) Vol. 135 Issue 18 Pg. 969-72 (May 01 1994) ISSN: 0030-6002 [Print] Hungary
• Vernacular Title: Atkaölö szer hatása a háziporra és a házipor allergiások tüneteire.
• PMID: 8190492 (Publication Type: Clinical Trial, English Abstract, Journal Article)

Chemical References

• Allergens
• Benzoates
• Dust
• Insecticides
• benzyl benzoate

Topics

• Acari (drug effects)
• Allergens
• Animals
• Asthma (drug therapy, etiology, immunology)
• Benzoates (pharmacology)
• Child
• Child, Preschool
• Dust
• Female
• Humans
• Insecticides (pharmacology)
• Male
• Mite Infestations (drug therapy, immunology)
• Rhinitis, Allergic, Perennial (drug therapy, immunology)