Popliteal Artery Entrapment Syndrome

Entrapment of the POPLITEAL ARTERY in the LEG due to an abnormal course of the artery often associated with onset of development and/or overuse of the gastrocnemius or popliteus muscles on the back of the leg. It is most often associated with runners and other athletes with enlarged calf muscle that compresses the POPLITEAL ARTERY.

Also Known As:

Networked: 131 relevant articles (2 outcomes, 12 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Ischemia
2.	Pain (Aches)
3.	Vascular Diseases (Vascular Disease)
4.	Medial Tibial Stress Syndrome
5.	Peripheral Arterial Disease

Experts

1.	Igari, Kimihiro: 3 articles (10/2021 - 01/2014)
2.	Inoue, Yoshinori: 3 articles (10/2021 - 01/2014)
3.	Hislop, Matthew: 3 articles (09/2017 - 01/2014)
4.	Hoshina, Katsuyuki: 2 articles (10/2021 - 10/2015)
5.	Scheltinga, Marc: 2 articles (01/2020 - 11/2019)
6.	Winkes, Michiel: 2 articles (01/2020 - 11/2019)
7.	van Eerten, Percy: 2 articles (01/2020 - 11/2019)
8.	Brodmann, Marianne: 2 articles (10/2019 - 01/2019)
9.	Tiesenhausen, Kurt: 2 articles (10/2019 - 01/2019)
10.	Cho, Yong-Pil: 2 articles (05/2018 - 09/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Popliteal Artery Entrapment Syndrome:

1.	phenyl-2-aminoethyl sulfide (PAES)IBA 10/01/2021 - "Larger studies, for which QISS is well suited, may be invaluable for distinguishing physiologic from pathologic arterial narrowing in patients with suspected popliteal artery entrapment syndrome (PAES)." 05/01/2018 - "The aim of this study was to analyze anatomical popliteal artery entrapment syndrome (PAES) and to individualize the treatment of this condition according to the anatomical status of the artery and the adjacent structure. " 10/01/2013 - "The purpose of this study was to report our experience with popliteal artery entrapment syndrome (PAES) with special emphasis on the applicability of duplex ultrasound scanning (DUS) when diagnosing PAES. " 01/01/2012 - "Of these, 30 studies were on popliteal artery entrapment syndrome (PAES). " 04/01/2011 - "This study reviews our experience with dynamic computed tomographic angiography (CTA) as an imaging modality in the evaluation of popliteal artery entrapment syndrome (PAES). "
2.	4- chloro- 3',6'- dimethyl- 2,2'- iminodibenzoate (TO 115)IBA 01/01/2015 - "Postoperative surveillance duplex US revealed a reduction of the PSV to 115 cm/sec. IDUS was very helpful in the operative management and intraoperative decision making process for popliteal artery entrapment. "
3.	Type A Botulinum Toxins (Botox)FDA Link 12/01/2018 - "Treatment of Functional Popliteal Artery Entrapment Syndrome with Ultrasound-Guided Botox Injection." 09/01/2017 - "Functional popliteal artery entrapment syndrome: use of ultrasound guided Botox injection as a non-surgical treatment option." 09/01/2017 - "Botulinum Toxin-A (BoNT-A) is an effective intervention for Functional Popliteal Artery Entrapment Syndrome (FPAES) however, concerns with this intervention include reductions in strength and performance. " 09/01/2017 - "To determine whether ultrasound-guided injection of botulinum toxin type A (BTX-A) is a viable alternative to surgical intervention for the treatment of functional popliteal artery entrapment syndrome (PAES). "
4.	CollagenIBA 01/01/1985 - "Although atherosclerosis was the most common diagnosis, other etiologies included thromboembolism, popliteal artery entrapment, Buerger's disease, collagen vascular disease, and arteritis. " 11/01/1985 - "Although premature atherosclerosis was the most common problem (50%), claudication or limb-threatening ischemia also resulted from other sources (thromboembolism, popliteal artery entrapment, Buerger's disease, collagen vascular disease, and Takayasu's arteritis). "
5.	Botulinum Toxins (Botulinum Toxin)IBA 09/01/2017 - "The effects of Botulinum Toxin injection in an elite sportsman with Functional Popliteal Artery Entrapment Syndrome: A case report." 06/01/2015 - "This case report suggests that botulinum toxin treatment could be an alternative to surgery for patients with functional popliteal artery entrapment syndrome. " 06/01/2015 - "Botulinum toxin as a treatment for functional popliteal artery entrapment syndrome."
6.	Polytetrafluoroethylene (Teflon)FDA Link 07/01/2017 - "The etiology of ischaemia was native artery thrombosis in 39 procedures (30,5%), PTFE graft thrombosis in 56 (43,8%), intra-stent thrombosis in 11 (8,6%), emboly in 9 (7%), popliteal aneurysm thrombosis in 9 (7%), vein graft thrombosis in 2 (1,6%) and popliteal artery entrapment in 2 (1,6%). "
7.	Anabolic Androgenic SteroidsIBA 04/18/2002 - "The popliteal-artery entrapment syndrome in a patient using anabolic steroids."
8.	incobotulinumtoxinAFDA Link 09/01/2017 - "Botulinum Toxin-A (BoNT-A) is an effective intervention for Functional Popliteal Artery Entrapment Syndrome (FPAES) however, concerns with this intervention include reductions in strength and performance. "
9.	cytoplasmic protein A (PACD)IBA 02/01/2022 - "Popliteal artery entrapment syndrome (PAES) and popliteal artery adventitial cystic disease (PACD) are two common nonatheromatous causes of claudication and critical limb ischemia. "
10.	A 19IBA 01/01/2010 - "The following is a case report of a 19 year old female, in whom popliteal artery entrapment syndrome was diagnosed, and successfully treated surgically. "

Therapies and Procedures

1.	Surgical Decompression 04/01/2004 - "The purpose of this study was to demonstrate whether there is postoperative improvement in blood flow in the affected limb after surgical decompression in popliteal artery entrapment syndrome (PAES). "
2.	Operative Surgical Procedures 10/01/2015 - "Careful examination of popliteal artery anatomy using imaging studies is essential for selecting the appropriate surgical procedure for popliteal artery entrapment syndrome. " 04/01/2016 - "Long-term outcomes of surgical procedures performed for popliteal artery entrapment syndrome can be considered satisfactory." 01/01/2015 - "We present a case series of 3 surgical procedures (2 patients) in which intraoperative duplex ultrasound (IDUS) was used to determine whether the chronic compression of the popliteal artery caused by popliteal artery entrapment syndrome had injured the artery to such a degree that interposition bypass was required. "
3.	Stents 04/06/2022 - "Popliteal Artery Entrapment Syndrome: A Rare Cause of Interwoven Nitinol Stent Fracture After Femoropopliteal Interventions." 07/01/2017 - "The etiology of ischaemia was native artery thrombosis in 39 procedures (30,5%), PTFE graft thrombosis in 56 (43,8%), intra-stent thrombosis in 11 (8,6%), emboly in 9 (7%), popliteal aneurysm thrombosis in 9 (7%), vein graft thrombosis in 2 (1,6%) and popliteal artery entrapment in 2 (1,6%). "
4.	Uterine Myomectomy 08/01/2002 - "Treatment of functional popliteal artery entrapment usually includes surgical exploration, release of the popliteal artery, and a myomectomy of the medial gastrocnemius head."
5.	Catheters 02/01/1997 - "To assess dynamic magnetic resonance angiography (MRA) as an alternative to catheter angiography in patients with popliteal artery entrapment syndrome (PAES). "