Functional popliteal artery entrapment syndrome: use of ultrasound guided Botox injection as a non-surgical treatment option.

Abstract

OBJECTIVE:

To determine whether ultrasound-guided injection of botulinum toxin type A (BTX-A) is a viable alternative to surgical intervention for the treatment of functional popliteal artery entrapment syndrome (PAES).

MATERIALS AND METHODS:

Twenty-seven patients met diagnostic criteria confirming the presence of functional PAES and agreed to go ahead with ultrasound-guided BTX-A injection at the level of artery occlusion. Patients were assessed and treated at baseline and given the option for 'top-up' injections at 6 and 12 months. Patients provided subjective symptom reports at 6 and 12 months post intervention.

RESULTS:

No patients reported being worse off after the intervention; 59% of patients were categorized as having a good response (i.e., initial improvement that was maintained at 12 months), 22% a mixed response (i.e., an initial improvement that subsequently reduced over 12 months) and 19% a poor response (i.e., no difference) to treatment.

CONCLUSIONS:

Ultrasound-guided BTX-A injection represents a viable alternative to surgery in the treatment of functional PAES. Further study will help determine the optimum dose and frequency of injection to prevent recurrence of symptoms.

• Authors: Matthew Hislop, Adam Brideaux, Sanjay Dhupelia
• Journal: Skeletal radiology (Skeletal Radiol) Vol. 46 Issue 9 Pg. 1241-1248 (Sep 2017) ISSN: 1432-2161 [Electronic] Germany
• PMID: 28600622 (Publication Type: Journal Article)

Chemical References

• Neuromuscular Agents
• Botulinum Toxins, Type A

Topics

• Adolescent
• Adult
• Aged
• Arterial Occlusive Diseases (drug therapy)
• Botulinum Toxins, Type A (therapeutic use)
• Female
• Humans
• Male
• Middle Aged
• Neuromuscular Agents (therapeutic use)
• Popliteal Artery
• Treatment Outcome
• Ultrasonography, Interventional