Vaccine Excipients

Media added to a vaccine for a specific purpose. These include: preservatives to prevent contamination, adjuvants to stimulate a stronger immune response, and stabilizers. (From https://www.cdc.gov/vaccines pubs/pinkbook/downloads/appendices/b/excipient-table-2.pdf)

Also Known As:

Networked: 9 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chiarella, Sergio E: 2 articles (02/2022 - 01/2022)
2.	Gonzalez-Estrada, Alexei: 2 articles (02/2022 - 01/2022)
3.	Joshi, Avni Y: 2 articles (02/2022 - 01/2022)
4.	Pitlick, Mitchell M: 2 articles (02/2022 - 01/2022)
5.	Beaumier, L: 1 article (05/2022)
6.	Huynh, V A: 1 article (05/2022)
7.	Janssen, C: 1 article (05/2022)
8.	D'Netto, Michael E: 1 article (02/2022)
9.	Dages, Kelley N: 1 article (02/2022)
10.	Park, Miguel A: 1 article (02/2022)

Related Diseases

1.	Hypersensitivity (Allergy) 05/01/2022 - "Conclusions: Specific allergological management should be offered to patients suspected of severe hypersensitivity to PEG and other vaccine excipients. " 01/01/2022 - "Allergic reactions to vaccines are rare and mostly due to vaccine excipient. " 01/01/2022 - "True, true, and unrelated: Stop routine testing to vaccine excipients for suspected vaccine allergy." 12/01/2021 - "Subsequent allergy testing of affected individuals has focused largely on evaluation of allergic sensitization to a novel vaccine excipient, polyethylene glycol (PEG). " 01/01/2023 - "To assess vaccine/excipient ST accuracy in predicting all-severity immediate allergic reactions upon re-vaccination, systematic review was performed searching Medline, EMBASE, Web of Science, and the WHO global coronavirus database (inception-Oct 4, 2021) for studies addressing immediate (≤4 h post-vaccination) all-severity allergic reactions to 2nd mRNA COVID-19 vaccination in persons with 1st dose immediate allergic reactions. "
2.	COVID-19 01/01/2022 - "Objective: To describe the clinical presentation, vaccine excipient skin testing results, and outcomes of subsequent COVID-19 vaccination in patients who experienced delayed systemic urticarial reactions after messenger RNA (mRNA) COVID-19 vaccination. " 01/01/2023 - "To assess vaccine/excipient ST accuracy in predicting all-severity immediate allergic reactions upon re-vaccination, systematic review was performed searching Medline, EMBASE, Web of Science, and the WHO global coronavirus database (inception-Oct 4, 2021) for studies addressing immediate (≤4 h post-vaccination) all-severity allergic reactions to 2nd mRNA COVID-19 vaccination in persons with 1st dose immediate allergic reactions. " 01/01/2023 - "Recent meta-analyses assessed the incidence of severe allergic reactions to initial COVID-19 vaccination, risk of mRNA-COVID-19 revaccination after an initial reaction, and diagnostic accuracy of COVID-19 vaccine and vaccine excipient testing in predicting reactions. " 01/01/2022 - "Conclusion: Delayed systemic urticarial reactions after mRNA COVID-19 vaccination were not life-threatening, could be treated with antihistamines, and were not predicted with vaccine excipient skin testing. "
3.	Urticaria (Hives) 09/01/2021 - "Though the most common cutaneous adverse reactions to vaccines are non-allergic, we believe the rash may represent an immediate hypersensitivity type I reaction against the vaccine excipient Polysorbate 80 (Pol80), configuring an acute allergic urticaria. "
4.	Immediate Hypersensitivity 09/01/2021 - "Though the most common cutaneous adverse reactions to vaccines are non-allergic, we believe the rash may represent an immediate hypersensitivity type I reaction against the vaccine excipient Polysorbate 80 (Pol80), configuring an acute allergic urticaria. "
5.	Exanthema (Rash) 09/01/2021 - "Though the most common cutaneous adverse reactions to vaccines are non-allergic, we believe the rash may represent an immediate hypersensitivity type I reaction against the vaccine excipient Polysorbate 80 (Pol80), configuring an acute allergic urticaria. "

Related Drugs and Biologics

1.	Messenger RNA (mRNA)
2.	Vaccines
3.	Polyethylene Glycols (Polyethylene Glycol)
4.	COVID-19 Vaccines
5.	Polysorbates (PSML)
6.	Histamine Antagonists (Antihistamines)