[ARN COVID-19 COMIRNATY Vaccine desensitization in a case of PEG Severe Immediate Hypersensitivity].

Abstract

Vaccination is the most efficient way to fight the Covid epidemic. However, suspicion of severe hypersensitivity to PEG (PolyEthylen Glycol) usually constitutes a vaccine contraindication. We report the case of a patient with a proven allergy to PEG and skin sensitization to the COMIRNATY vaccine (PEG in its composition). He was able to benefit from the vaccine under the 5-step desensitization protocol. Conclusions: Specific allergological management should be offered to patients suspected of severe hypersensitivity to PEG and other vaccine excipients. We propose a solution for Comirnaty administration for patients with a proven severe allergy to PEG.

• Authors: V A Huynh, C Janssen, L Beaumier
• Journal: Revue francaise d'allergologie (2009) (Rev Fr Allergol (2009)) Vol. 62 Issue 4 Pg. 431-434 (May 2022) ISSN: 1877-0312 [Print] Netherlands
• Vernacular Title: Induction de tolérance au vaccin à ARN COMIRNATY chez un patient avec une hypersensibilité allergique sévère au PEG.
• PMID: 34484471 (Publication Type: English Abstract, Journal Article)
• Copyright: © 2021 Elsevier Masson SAS. All rights reserved.