Sulfathiazole

A sulfathiazole compound that is used as a short-acting anti-infective agent. It is no longer commonly used systemically due to its toxicity, but may still be applied topically in combination with other drugs for the treatment of vaginal and skin infections, and is still used in veterinary medicine.

Also Known As:

Alphadol; N(1)-2-thiazolylsulfanilamide; Norsulfazole; Sulfathiazole Sodium; Sulfathiazole, Monosodium Salt; 4-amino-N-2-thiazolyl Benzenesulfonamide; Benzenesulfonamide, 4 amino N 2 thiazolyl; Benzenesulfonamide, 4-amino-N-2-thiazolyl

Networked: 149 relevant articles (10 outcomes, 4 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Kabra, Sushil K: 2 articles (08/2013 - 07/2008)
2.	Lodha, Rakesh: 2 articles (08/2013 - 07/2008)
3.	Choi, Kyungho: 2 articles (01/2009 - 01/2008)
4.	Kim, Jungkon: 2 articles (01/2009 - 01/2008)
5.	Balasubramaniyan, Sakthivel: 1 article (05/2022)
6.	Irfan, Navabshan: 1 article (05/2022)
7.	Nagendran, Saraswathy: 1 article (05/2022)
8.	Kumar, Abhinit: 1 article (01/2021)
9.	Kumar, Sunil: 1 article (01/2021)
10.	Loharch, Saurabh: 1 article (01/2021)

Related Diseases

1.	Infections 03/10/1956 - "[Use of sulfathiazole collyrium in infections of the eye and its adnexa]." 04/01/1944 - "Two monkeys, one receiving sulfathiazole on the 2nd day of acute infection and the other on the 4th day, had no immunity at the time of reinoculation, 3 weeks and 10 weeks later, respectively. " 03/01/1946 - "A study of the value of local sulfathiazole in operative wounds in the prophylaxis of infection." 12/01/1990 - "Clearance of sulfobromophthalein or sulfathiazole from the plasma of lambs was unaffected by infection with H contortus. " 04/01/1984 - "Comparative efficacy of sulfamethazine and sulfathiazole in feed for control of Bordetella bronchiseptica infection in swine."
2.	Pneumonia (Pneumonitis) 10/01/1950 - "Treatment of pneumonias in children with a single massive dose of sulfathiazole." 01/01/1947 - "On the treatment of pneumonia in children with one massive dose of sulfathiazole." 09/01/1940 - "ANTIBODY FORMATION IN CASES OF LOBAR PNEUMONIA TREATED WITH SULFATHIAZOLE." 04/15/1948 - "Treatment of pneumonia with shock dose of sulfathiazole illustrated in 688 cases." 08/14/2013 - "The one trial that showed an increase in the rate of pneumonia with antibiotics was conducted in 1942 and compared oral sulfathiazole with symptomatic treatment. If the results of this trial are removed from the meta-analysis, there is a statistically significant reduction in the incidence of pneumonia in children receiving antibiotics (OR 0.26; 95% CI 0.12 to 0.60). "
3.	Anuria 03/02/1950 - "[Anuria following a single subcutaneous dose of sulfathiazole]." 04/01/1948 - "Decapsulation of the kidney for anuria due to sulfathiazole." 11/01/1946 - "Sulfathiazole anuria with recovery following renal decapsulation." 09/01/1941 - "Sulfathiazole Anuria with Recovery." 07/29/1948 - "Complications for sulfathiazole treatment; two cases of agranulocytosis and anuria."
4.	Vaginitis 04/25/1956 - "[Treatment of mucopurulent discharge in bacterial cervicitis and vaginitis with ovules of sulfathiazole]." 07/01/1960 - "Veneral prophylaxis for women: use of a sulfathiazole-soap applicator for prophylaxis and treatment of vaginitis." 01/01/2016 - "We conclude that the prophylactic use of low doses of doxycycline, oxytetracycline, or sulfathiazole in intravaginal sponges used for synchronization of estrus helps to reduce clinical vaginitis in dairy goats and does not seem to be the cause of positive results in microbial inhibitor tests used to detect antibiotics in goat milk. "
5.	Brucellosis (Malta Fever) 08/01/1948 - "Acute undulant fever relieved by combined sulfadiazine and sulfathiazole." 08/01/1951 - "[Practical, clinical and etiopathogenic observations on 7 cases of brucellosis treated with streptomycin, PAS and sulfathiazole]." 11/01/1952 - "[Effective therapy of severe brucellosis with streptomycin associated with sulfathiazole]."

Related Drugs and Biologics

1.	Anti-Bacterial Agents (Antibiotics)
2.	Penicillins (Penicillin)
3.	Sulfadiazine (Sulphadiazine)
4.	Chloramphenicol (Chloromycetin)
5.	Sulfamethazine (Sulfadimidine)
6.	Sulfamerazine
7.	Oxytetracycline (Terramycin)
8.	Gentamicins (Gentamicin)
9.	Dihydrostreptomycin Sulfate (Dihydrostreptomycin)
10.	Sulfobromophthalein (Sulfobromophthalein Sodium)

Related Therapies and Procedures

1.	Ovariectomy (Oophorectomy)
2.	Therapeutics
3.	Drug Therapy (Chemotherapy)
4.	Punctures
5.	Enema (Enemas)