Contraindications

A condition or factor associated with a recipient that makes the use of a drug, procedure, or physical agent improper or inadvisable. Contraindications may be absolute (life threatening) or relative (higher risk of complications in which benefits may outweigh risks).

Also Known As:

Contraindications, Physical Agent; Medical Contraindications; Agent Contraindication, Physical; Agent Contraindications, Physical; Contraindication; Contraindication, Medical; Contraindication, Physical Agent; Contraindications, Medical; Medical Contraindication; Physical Agent Contraindication; Physical Agent Contraindications

Networked: 14439 relevant articles (475 outcomes, 759 trials/studies)

Relationship Network

Therapy Context: Research Results

Therapeutics: 1158551
- Contraindications: 14439
  - Drug Contraindications: 24
  - Procedure Contraindications: 8

Experts

1.	Fonarow, Gregg C: 20 articles (06/2022 - 09/2006)
2.	Sievert, Horst: 18 articles (01/2022 - 12/2003)
3.	Peterson, Eric D: 14 articles (10/2016 - 07/2005)
4.	Aronow, Wilbert S: 13 articles (10/2016 - 01/2002)
5.	Hernandez, Adrian F: 10 articles (01/2022 - 02/2009)
6.	Schmidt, Boris: 10 articles (01/2021 - 12/2013)
7.	Brugada, Pedro: 10 articles (11/2019 - 06/2010)
8.	Freixa, Xavier: 9 articles (01/2022 - 07/2013)
9.	Chierchia, Gian-Battista: 9 articles (11/2019 - 07/2015)
10.	Ströker, Erwin: 9 articles (11/2019 - 07/2015)

Related Diseases

1.	Neoplasms (Cancer) 05/01/2021 - "A recent history of malignancy is an absolute contraindication for lung transplantation according to the International Society of Heart and Lung Transplantation; however, a 5-year disease-free interval should be demonstrated in most cases of malignancies to consider the patient a suitable recipient. " 11/01/2014 - "Thoracic surgery has been shown to be safe in selected elderly patients, and age should not be a contraindication to a therapy that offers the best chance of cure for patients with early-stage cancer. " 08/01/2009 - "Thoracic surgery has been shown to be safe in selected elderly patients, and age should not be a contraindication to a therapy that offers the best chance of cure for early stage cancer patients. " 12/10/2004 - "Fifteen premenopausal women out of 31 (51.6%) received systemic HRT on the basis of age (<45 years), absence of medical contraindication or subjective refusal, and complete remission of underlying malignancies post-SCT. " 01/01/2023 - "Surgical excision of JPs is a safe and effective strategy, and early surgical treatment is a good option for patients with C1-2 tumors without surgical contraindications."
2.	Hemorrhage 04/01/2020 - "Based on this economic model, for AHA patients with high titres who were bleeding, aPCC was the most cost-effective treatment option and may be considered for use if there is no clinical contraindication." 03/01/1995 - "Age alone is not a contraindication for thrombolysis because the risk of bleeding complications in the elderly is outweighed by a significant improvement in mortality. " 10/01/2018 - "For complications of all patients, there was no mortality and major bleeding occurred.PMT could be a safe and effective management for DVT patients with relative contraindications, and the acute DVT may achieve better outcomes when they receive CDT or PMT." 08/01/2013 - "However, the possibility of an improved neurologic outcome outweighs the risk of bleeding, although major surgery may be a relative contraindication for TH. " 08/01/2012 - "However, it was associated with an increased efficiency of care and potentially improved control of hemorrhage in higher risk patients, supporting the routine use of early endoscopy unless specific contraindications exist. "
3.	Stroke (Strokes) 09/01/2012 - "The paper also reviews the potential for t-PA to be given by more physicians, in remote regions using Telestroke, the possibility for using imaging characteristics rather than the onset of stroke as a determinant of eligibility for t-PA, the status of contraindications for thrombolysis, and the possibility of combining t-PA with immune modulation for improved stroke outcomes." 09/01/2022 - "Intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) can be effective when initiated in an acute stroke, but their benefit is time-dependent and their use may be restricted by contraindications (CIs) such as anticoagulation therapy. " 03/01/2016 - "Endovascular reperfusion therapy has shown promising results in recent trials for community-onset strokes (COS) and is limited by less contraindications than systemic thrombolysis. " 04/01/2021 - "The objective of this study was to evaluate the efficacy of MT without IVT in patients with no contraindications to IVT presenting directly to a tertiary stroke center with acute anterior circulation LVO. " 06/01/2014 - "A few studies have validated the efficacy of LARIAT in mitigating stroke risk in AF patients with contraindications to anticoagulation. "
4.	Pain (Aches) 01/01/2011 - "The combination of these two minimally invasive interventions is particularly effective for severe leg pain and LBP in elderly patients or medically compromised cases with contraindications against general anesthesia, as well as in patients with FBSS." 08/01/2017 - "Thoracic epidural analgesia (EPI) is the "gold standard" for postthoracotomy pain, but especially in lung transplantation contraindications, and potential infectious complications limit its advantages. " 07/01/2014 - "In absence of obstetrical contraindication, neuraxial analgesia has to be considered as the gold standard in obtaining maternal pain relief during labour. " 12/01/2000 - "TT should be improved by shortening pain-to-door time, broadening indications, and limiting contraindications." 01/01/2019 - "Exclusion criteria were radicular pain, nonmechanical causes of pain, contraindications for UD, or the patient received other LBP therapy during the study. "
5.	Obesity 11/01/2023 - "With no significant increase in revision rates after a UKA, a significantly greater improvement in Oxford Knee Scores and no differences Knee Society Scores or Visual Analogue Scales, obesity should no longer be viewed as a relative contraindication when performing unicompartmental knee replacements." 04/01/2021 - "Obesity is not a contraindication to good outcomes from laparoscopic surgery." 10/01/2013 - "The laparoscopic approach is safe and effective for defects larger than 3 cm in diameter; old age, obesity, previous abdominal operations, recurrence and strangulation are not absolute contraindications. " 01/01/2004 - "Although obesity was initially considered a relative contraindication for laparoscopy, the retroperitoneal approach has been reported to be safe and effective for such patients during renal and adrenal surgery. " 03/01/2023 - "Although obesity has historically been described as a contraindication to UKA, improved outcomes with modern UKA implant designs have challenged this perception. "

Related Drugs and Biologics

1.	Anticoagulants
2.	Adrenal Cortex Hormones (Corticosteroids)
3.	Aspirin (Acetylsalicylic Acid)
4.	Steroids
5.	Metformin (Glucophage)
6.	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)
7.	Heparin (Liquaemin)
8.	Diuretics
9.	Rituximab (Mabthera)
10.	Warfarin (Coumadin)

Related Therapies and Procedures

1.	Therapeutics
2.	Thrombolytic Therapy
3.	Radiotherapy
4.	Drug Therapy (Chemotherapy)
5.	Liver Transplantation