Interleukin-1 Receptor-Like 1 Protein

A receptor for INTERLEUKIN-33 that is related structurally to the interleukin-1 receptor. It contains three extracellular IMMUNOGLOBULIN-LIKE DOMAIN regions and associates with INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN upon binding IL-33 to initiate signaling. It may function in the response of HELPER T CELLS to INFLAMMATION.

Also Known As:

IL1RL1 Protein; Interleukin 1 Receptor-Related Protein; Interleukin-33 Receptor; Interleukin 1 Receptor Like 1 Protein; Interleukin 1 Receptor Related Protein; Interleukin 33 Receptor; Receptor, Interleukin-33

Networked: 10 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Immunologic Receptors: 9
        Cytokine Receptors: 1620
        Interleukin Receptors: 114
        Interleukin-1 Receptors: 3600
        Interleukin-1 Receptor-Like 1 Protein: 10
        human IL1RL1 protein
        mouse Il1rl1 protein

Experts

1.	Chen, Yun-Da: 1 article (01/2022)
2.	Li, Mi: 1 article (01/2022)
3.	Li, Shu: 1 article (01/2022)
4.	Shu, Hong-Bing: 1 article (01/2022)
5.	Yi, Xue-Mei: 1 article (01/2022)
6.	Fontes-Carvalho, Ricardo: 1 article (08/2021)
7.	Martins da Costa, Ana: 1 article (08/2021)
8.	Pedro Nunes, José: 1 article (08/2021)
9.	Sampaio, Francisco: 1 article (08/2021)
10.	Tavares, Ana: 1 article (08/2021)

Related Diseases

1.	Heart Failure 08/10/2021 - "Interleukin 1 receptor related protein, Suppression of tumorigenicity 2 (ST2) is a biomarker related to the pathophysiology of fibrosis, having shown promise in the study of heart failure. " 09/05/2023 - "Interleukin-1 receptor-like 1 (IL1RL1) protein and human/Soluble suppression of tumorigenesis-2 (sST2) are promising biomarkers for heart failure (HF). "
2.	Fibrosis (Cirrhosis) 08/10/2021 - "Interleukin 1 receptor related protein, Suppression of tumorigenicity 2 (ST2) is a biomarker related to the pathophysiology of fibrosis, having shown promise in the study of heart failure. "
3.	Dengue (Dengue Fever) 03/01/2014 - "In this study, the levels of TNF-α, IL-6, IL-1, IL-17, soluble interleukin-1 receptor like 1 protein (sST2), soluble TNF-related apoptosis-inducing ligand (sTRAIL), IL-12 and soluble receptors for TNF (sTNF-RI and sTNF-RII) were determined by ELISA in dengue patients and monocyte/macrophage cultures. "
4.	Myalgia 03/01/2020 - "Nociceptor Interleukin 33 Receptor/ST2 Signaling in Vibration-Induced Muscle Pain in the Rat."
5.	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 12/01/2017 - "Interleukin 1 Receptor-Like 1 Protein (ST2) is a Potential Biomarker for Cardiomyopathy in Duchenne Muscular Dystrophy."

Related Drugs and Biologics

1.	Biomarkers (Surrogate Marker)
2.	TNF-Related Apoptosis-Inducing Ligand
3.	Interleukin-17 (Interleukin 17)
4.	Interleukin-12 (IL 12)
5.	Interleukin-6 (Interleukin 6)
6.	Interleukin-1 (Interleukin 1)
7.	Interleukin-1 Receptors (Interleukin 1 Receptor)
8.	Cytokines
9.	Interferons