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N- (2- (piperidin- 1- yl)phenyl)- 2- (thiophen- 2- yl)- 1H- benzo(d)imidazole- 4- carboxamide

structure in first source

Also Known As:

CXI-benzo-84

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Aniline Compounds: 46
    - Anilides: 22
      - N-(2-(piperidin-1-yl)phenyl)-2-(thiophen-2-yl)-1H-benzo(d)imidazole-4-carboxamide: 1
- Amides: 2428
  - Anilides: 22
    - N-(2-(piperidin-1-yl)phenyl)-2-(thiophen-2-yl)-1H-benzo(d)imidazole-4-carboxamide: 1
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzimidazoles: 245
      - N-(2-(piperidin-1-yl)phenyl)-2-(thiophen-2-yl)-1H-benzo(d)imidazole-4-carboxamide: 1

Experts

1.	Gupta, Tilak Kumar: 1 article (08/2013)
2.	Kini, Sudarshan: 1 article (08/2013)
3.	Kunwar, Ambarish: 1 article (08/2013)
4.	Panda, Dulal: 1 article (08/2013)
5.	Rai, Ankit: 1 article (08/2013)
6.	Surolia, Avadhesha: 1 article (08/2013)

Related Diseases

1.

Neoplasms (Cancer)

08/01/2013 - "CXI-benzo-84 inhibited cell cycle progression in metaphase stage of mitosis and accumulated spindle assembly checkpoint proteins Mad2 and BubR1 on kinetochores, which subsequently activated apoptotic cell death in cancer cells. "
08/01/2013 - "CXI-benzo-84 reversibly binds to tubulin at colchicine site and induces apoptosis in cancer cells."
08/01/2013 - "In addition to its potential use in cancer chemotherapy, CXI-benzo-84 may also be useful to screen colchicine-site agents and to understand the colchicine binding site on tubulin. "

Related Drugs and Biologics

1.	Tubulin
2.	Proteins (Proteins, Gene)
3.	Colchicine

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)