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2-cyanobenzothiazole

structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Nitriles: 227
  - 2-cyanobenzothiazole: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - Benzothiazoles: 40
        2-cyanobenzothiazole: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzothiazoles: 40
      - 2-cyanobenzothiazole: 2

Experts

1.	Liu, Bin: 1 article (02/2022)
2.	Liu, Jingjing: 1 article (02/2022)
3.	Liu, Xingang: 1 article (02/2022)
4.	Qi, Guobin: 1 article (02/2022)
5.	Shi, Leilei: 1 article (02/2022)
6.	Wu, Min: 1 article (02/2022)
7.	Cao, Ziyang: 1 article (01/2022)
8.	Li, Dongdong: 1 article (01/2022)
9.	Liu, Mengting: 1 article (01/2022)
10.	Luo, Yingli: 1 article (01/2022)

Related Diseases

1.

Neoplasms (Cancer)

01/01/2022 - "After extravasating into the tumor site, the slightly acidic microenvironment induces the exposure of cysteine on the nanoparticle surface, which subsequently undergoes a bioorthogonal reaction with the 2-cyanobenzothiazole group of another neighboring nanoparticle, enabling the formation of micro-sized drug depots to enhance drug retention and enrichment. "
02/01/2022 - "Upon tumor-specific cathepsin protease reaction, the cleavage of peptides induces condensate polymerization between the exposed cysteine and 2-cyanobenzothiazole on 3CBT, triggering accumulation of D2P1 into the tumor site, leading to fluorescence light-up. "

Related Drugs and Biologics

1.	Cysteine (L-Cysteine)
2.	Peptides (Polypeptides)
3.	Peptide Hydrolases (Proteases)
4.	Cathepsins