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balanophonin

from fruit wall of Cirsium vulgare; structure in first source

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzyl Compounds: 2
        Lignans: 1113
        balanophonin: 5

Experts

1.	Chang, Fang-Pin: 1 article (09/2018)
2.	Chao, Wei: 1 article (09/2018)
3.	Chen, Jih-Jung: 1 article (09/2018)
4.	Cheng, Ming-Jen: 1 article (09/2018)
5.	Huang, Guan-Jhong: 1 article (09/2018)
6.	Huang, Hui-Chi: 1 article (09/2018)
7.	Kuo, Yueh-Hsiung: 1 article (09/2018)
8.	Sung, Ping-Jyun: 1 article (09/2018)
9.	Wang, Sheng-Yang: 1 article (09/2018)
10.	Baghy, Kornélia: 1 article (06/2018)

Related Diseases

1.	Neoplasms (Cancer) 09/01/2017 - "Balanophonin, a natural neolignoid from Firmiana simplex, has been reported to have anti-inflammatory and anti-cancer effects. " 07/01/2008 - "This new lignan glycoside, along with its aglycone, (7'S, 8'R)-dihydrodehydrodiconiferyl alcohol (3), and another lignan with a similar skeleton, (-)-balanophonin (2), which have been previously isolated from this plant, were evaluated for cytotoxicity in human cancer cell lines such as HeLa, MCF-7, SK-MEL-5, and SK-OV-3. "
2.	Hepatocellular Carcinoma (Hepatoma) 09/08/2018 - "Compounds 1⁻13 were evaluated using an in-vitro MTT cytotoxic assay for hepatocellular carcinoma (HCC) cells, and the preliminary results showed that ficusal (10), balanophonin (11), and p-coumaric acid (13) exhibited moderate cytotoxic activity, with EC50 values of 85.36 ± 4.36, 92.63 ± 1.41, and 29.18 ± 3.48 µg/mL against Hep3B cells, respectively." 05/01/2003 - "A new cassane diterpene, dipteryxic acid (1), and a new isoflavonolignan, 5-methoxyxanthocercin A (2), as well as four known active compounds, isoliquiritigenin (3), 6,4'-dihydroxy-3'-methoxyaurone (4), sulfuretin (5), and (+/-)-balanophonin (6), and five known inactive compounds, butin, eriodictyol, 7-hydroxychromone, 7,3'-dihydroxy-8,4'-dimethoxyisoflavone, and (-)-lariciresinol, were isolated from an ethyl acetate-soluble extract of the seeds of Dipteryx odorata, using a bioassay based on the induction of quinone reductase (QR) in cultured Hepa 1c1c7 mouse hepatoma cells to monitor chromatographic fractionation. "
3.	Colonic Neoplasms (Colon Cancer) 06/01/2018 - "The antiproliferative assay of the compounds isolated from their optimum sources, confirmed a dose-dependent inhibitory effect of the structures bearing the 4',7-epoxy moiety (balanophonin, picrasmalignan, desmethyl balanophonin, desmethyl picrasmalignan) against SW480 colon cancer cells, while those bearing the 4',7-dihydroxy motif (prebalanophonin, prepicrasmalignan) were inactive."

Related Drugs and Biologics

1.	Lignans
2.	NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)
3.	Glycosides
4.	Diterpenes
5.	p-coumaric acid
6.	5-methoxyxanthocercin A
7.	dipteryxic acid
8.	ficusal
9.	lariciresinol
10.	sulfuretin