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1,4-lactone D-Glucaric acid

an antidiabetic agent

Also Known As:

D-Glucaric acid, 1,4-lactone; D-saccharic acid-1,4-lactone; glucaric acid 1,4-lactone; saccharic acid-1,4-lactone

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Lactones: 1549
  - 1,4-lactone D-Glucaric acid: 3
- Carboxylic Acids: 973
  - Hydroxy Acids: 94
    - Sugar Acids: 4
      - Glucaric Acid: 70
        1,4-lactone D-Glucaric acid: 3
  - Acyclic Acids
    - Sugar Acids: 4
      - Glucaric Acid: 70
        1,4-lactone D-Glucaric acid: 3
Carbohydrates: 22023
- Sugar Acids: 4
  - Glucaric Acid: 70
    - 1,4-lactone D-Glucaric acid: 3

Experts

1.	Bhattacharya, Semantee: 2 articles (02/2013 - 12/2011)
2.	Gachhui, Ratan: 2 articles (02/2013 - 12/2011)
3.	Sil, Parames C: 2 articles (02/2013 - 12/2011)
4.	Manna, Prasenjit: 1 article (12/2011)
5.	Gan, Xuhua: 1 article (02/2010)
6.	Tan, Huarong: 1 article (02/2010)
7.	Tang, Xinyun: 1 article (02/2010)
8.	Wang, Kan: 1 article (02/2010)
9.	Wang, Shuo: 1 article (02/2010)

Related Diseases

1.	Diabetes Mellitus 12/01/2011 - "D-saccharic acid-1,4-lactone ameliorates alloxan-induced diabetes mellitus and oxidative stress in rats through inhibiting pancreatic β-cells from apoptosis via mitochondrial dependent pathway."
2.	Neoplasms (Cancer) 02/01/2010 - "D-saccharic acid-1,4-lactone (DSL), a component of kombucha, inhibits the activity of glucuronidase, an enzyme indirectly related with cancers. "
3.	Hyperglycemia 02/01/2013 - "The prophylactic role of D-saccharic acid-1,4-lactone against hyperglycemia-induced hepatic apoptosis via inhibition of both extrinsic and intrinsic pathways in diabetic rats."

Related Drugs and Biologics

1.	Alloxan
2.	Glucuronidase
3.	Enzymes