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5- (4- bromobenzyloxy)- 2- (2- (5- methoxyindolyl)ethyl- 1- carbonyl)- 4H- chromen- 4- one

inhibits breast cancer resistance protein; structure in first source

Also Known As:

MBL-II-141

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        5-(4-bromobenzyloxy)-2-(2-(5-methoxyindolyl)ethyl-1-carbonyl)-4H-chromen-4-one: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - 5-(4-bromobenzyloxy)-2-(2-(5-methoxyindolyl)ethyl-1-carbonyl)-4H-chromen-4-one: 1
    - Benzopyrans: 195
      - Chromones: 159
        5-(4-bromobenzyloxy)-2-(2-(5-methoxyindolyl)ethyl-1-carbonyl)-4H-chromen-4-one: 1

Experts

1.	Bouard, Charlotte: 1 article (12/2014)
2.	Boumendjel, Ahcène: 1 article (12/2014)
3.	Di Pietro, Attilio: 1 article (12/2014)
4.	Gauthier, Charlotte: 1 article (12/2014)
5.	Gervot, Héloïse: 1 article (12/2014)
6.	Guitton, Jérôme: 1 article (12/2014)
7.	Honorat, Mylène: 1 article (12/2014)
8.	Lecerf-Schmidt, Florine: 1 article (12/2014)
9.	Payen, Léa: 1 article (12/2014)
10.	Peres, Basile: 1 article (12/2014)

Related Diseases

1.	Neoplasms (Cancer) 12/15/2014 - "Combination of 10 mg/kg MBL-II-141 with the anticancer agent CPT-11 completely blocked the growth of 90% freshly implanted ABCG2-positive tumors. "
2.	Glioma (Gliomas) 12/15/2014 - "MBL-II-141 strongly increased CPT-11 levels in the brain, and therefore would be a valuable agent to improve drug distribution into the brain to efficiently treat aggressive gliomas. "

Related Drugs and Biologics

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