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phenyl acetate

The ester formed between phenol and acetic acid. Don't confuse with phenylacetic acid derivatives listed under PHENYLACETATES.

Also Known As:

acetic acid, phenyl ester; phenol acetate

Networked: 19 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        phenyl acetate: 19
- Carboxylic Acids: 973
  - Acyclic Acids
    - Acetates: 4994
      - phenyl acetate: 19
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Acetates: 4994
      - phenyl acetate: 19

Experts

1.	Barbosa, Décio Sabbatini: 1 article (02/2022)
2.	Kanchanatawan, Buranee: 1 article (02/2022)
3.	Limotai, Chusak: 1 article (02/2022)
4.	Maes, Michael H J: 1 article (02/2022)
5.	Matsumoto, Andressa Keiko: 1 article (02/2022)
6.	Michelin, Ana Paula: 1 article (02/2022)
7.	Moreira, Estefânia Gastaldello: 1 article (02/2022)
8.	Supasitthumrong, Thitiporn: 1 article (02/2022)
9.	de Lima Pedrão, João Victor: 1 article (02/2022)
10.	de Oliveira Semeão, Laura: 1 article (02/2022)

Related Diseases

1.	Lung Neoplasms (Lung Cancer) 06/01/2011 - "In the present study, we evaluated the in vitro cytotoxic activity of new acetoxycoumarin derivatives: 4-(7-methoxy-4-methyl-2-oxo-2H-chromen-3-yl)phenyl acetate (1), 4-(1-methyl-3-oxo-3H-benzo[f]chromen-2-yl)phenyl acetate (2), 4-(6-propionamido-4-methyl-2-oxo-2H-chromen-3-yl) phenyl acetate (3), 4-(7-acetoxy-2-oxo-4-phenyl-2H-chromen-3-yl)phenyl acetate (4), 4-(2-oxo-4-phenyl-2H-chromen-3-yl)phenyl acetate (5), 4-(6-bromo-2-oxo-4-phenyl-2H-chromen-3-yl)phenyl acetate (6), 4-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)phenyl acetate (7), 4-(6,8-dibromo-4-methyl-2-oxo-2H-chromen-3-yl)phenyl acetate (8) against A549 human lung cancer, CRL 1548 rat liver cancer and CRL 1439 normal rat liver cells. "
2.	Liver Neoplasms (Liver Cancer) 06/01/2011 - "In the present study, we evaluated the in vitro cytotoxic activity of new acetoxycoumarin derivatives: 4-(7-methoxy-4-methyl-2-oxo-2H-chromen-3-yl)phenyl acetate (1), 4-(1-methyl-3-oxo-3H-benzo[f]chromen-2-yl)phenyl acetate (2), 4-(6-propionamido-4-methyl-2-oxo-2H-chromen-3-yl) phenyl acetate (3), 4-(7-acetoxy-2-oxo-4-phenyl-2H-chromen-3-yl)phenyl acetate (4), 4-(2-oxo-4-phenyl-2H-chromen-3-yl)phenyl acetate (5), 4-(6-bromo-2-oxo-4-phenyl-2H-chromen-3-yl)phenyl acetate (6), 4-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)phenyl acetate (7), 4-(6,8-dibromo-4-methyl-2-oxo-2H-chromen-3-yl)phenyl acetate (8) against A549 human lung cancer, CRL 1548 rat liver cancer and CRL 1439 normal rat liver cells. "
3.	Carcinoma (Carcinomatosis) 07/01/2018 - "In this study, p53 variant human colon carcinoma cell lines were chronically exposed to varying concentrations of the endogenous metabolites-phenyl acetate, ursodeoxycholate, and tauroursodeoxycholate-to determine the role of p53-induced cytotoxicity, with p53 mutant and deficient cell lines representing precancerous lesions. "
4.	Neoplasms (Cancer) 08/01/2009 - "The novel molecule 2-[5-(2-chloroethyl)-2-acetoxy-benzyl]-4-(2-chloroethyl)-phenyl acetate inhibits phosphoinositide 3-kinase/Akt/mammalian target of rapamycin signalling through JNK activation in cancer cells." 03/01/1984 - "The modified steroidal alkylating agent 3 beta-hydroxy-13 alpha-amino-13,17-seco-5 alpha-androstan-17-oic-13,17-lactam [p-[bis(2-chloroethyl)amino]phenyl]acetate (NSC 290205) is active in treating the LX-1 lung and MX-1 breast xenografts as well as a number of rodent tumors. " 01/01/1982 - "The modified steroidal alkylating agent, 3 beta-hydroxy-13 alpha-amino-13,17-seco-5 alpha-androstane-17-oic-13,17-lactam[p-[bis(2-chloroethyl)amino]-phenyl]acetate showed excellent activity in treatment of there murine solid tumors. " 05/01/2006 - "An androsterone D-lactam steroidal ester, the 3beta-hydroxy-13alpha-amino-13,17-seco- 5alpha-androstan-17-oic-13,17-lactam, p-bis(2-chloroethyl)amino phenyl acetate (lactandrate) was synthesized and tested for antitumor activity against six human breast cancer cell lines in vitro and against two murine and one xenograft mammary tumors in vivo. "
5.	Coronary Disease (Coronary Heart Disease) 03/01/2019 - "Low serum PON1 activities (paraoxon, phenyl-acetate or lactone substrates) are associated with coronary heart disease (CHD). " 05/01/2015 - "Paraoxonase 1 (PON1) is an important hydrolase, and the enzyme activity decreases in patients with liver disease, diabetes, coronary heart disease, etc. Phenyl acetate and organophosphates are usually employed as substrates for serum PON1 activity assay. "

Related Drugs and Biologics

1.	Acetates (Acetic Acid Esters)
2.	ursodoxicoltaurine
3.	Paraoxon (E600)
4.	Aryldialkylphosphatase (Paraoxonase)
5.	Lactams
6.	Alkylating Agents
7.	TOR Serine-Threonine Kinases
8.	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
9.	Phenol (Carbolic Acid)
10.	N-Acetylneuraminic Acid (Sialic Acid)

Related Therapies and Procedures

1.	Peritoneal Dialysis
2.	Renal Dialysis (Hemodialysis)