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Phenol (Carbolic Acid)

An antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. It has been used to disinfect skin and to relieve itching. (From Martindale, The Extra Pharmacopoeia, 30th ed, p801)

Also Known As:

Carbolic Acid; Hydroxybenzene; Phenol, Sodium Salt; Acid, Carbolic; Sodium Salt Phenol

Networked: 1242 relevant articles (58 outcomes, 91 trials/studies) for this Drug, Comments

Relationship Network

Drug Context: Research Results

Organic Chemicals: 49
- Phenols: 243
  - Phenol: 1242

Experts

1.	Campese, Vito M: 4 articles (09/2003 - 02/2002)
2.	Kudavalli, Jaya Satyanarayana: 2 articles (08/2012 - 12/2011)
3.	Boyd, Derek R: 2 articles (08/2012 - 12/2011)
4.	Otto, Michael: 2 articles (04/2012 - 01/2005)
5.	Losa Iglesias, M E: 2 articles (03/2012 - 08/2010)
6.	Becerro de Bengoa Vallejo, R: 2 articles (03/2012 - 08/2010)
7.	Hasumi, Keiji: 2 articles (01/2012 - 01/2010)
8.	Vullo, Daniela: 2 articles (03/2011 - 10/2009)
9.	Supuran, Claudiu T: 2 articles (03/2011 - 10/2009)
10.	Tatlican, Semih: 2 articles (03/2010 - 08/2009)

Related Diseases

1.	Pain (Aches) 09/01/2012 - "The mean total dose for the lower limb muscle was 93.8 ± 63.5 U, and phenol volume was 4.1 ± 1.3 ml. There was a significant improvement in Ashworth Scale and pain scores. " 05/01/1992 - "Two weeks after the lower thoracic pain was relieved, the patient had complained of a new right-sided pain in the region of C7-T2, which was treated successfully with 10 ml 10% phenol. " 10/01/2005 - "Alcoholization with phenol in the percutaneous treatment of IDN has the purpose of provoking a permanent chemical neurolysis, obtaining remission of the neuritic pain symptoms. " 06/01/1989 - "Evaluation of neurolytic blocks using phenol and cryogenic block in the management of chronic pain." 10/01/1980 - "The effects of subarachnoid phenol blockade have been evaluated on the basis of pain relief (measured by the visual analogue test) and improved general well being. " Order ALL the reference details at left...
2.	Neoplasms (Cancer) 11/02/2006 - "The most potent inhibitor, 4-[(3,5-diamino-1H-pyrazol-4-yl)diazenyl]phenol 31b (CAN508), reduced the frequency of S-phase cells of the cancer cell line HT-29 in antiproliferation assays. " 05/15/2012 - "Natural phenol licorice compounds have been shown to induce apoptosis in cancer cells. " 05/01/2009 - "Positive staining of tumor cells and/or endothelial cells by the TUNEL method was found in phenol-treated lesions, but not in nontreated lesions. " 05/01/2009 - "Phenol treatment induced a strong degeneration of tumor cells and endothelial cells in the dermis, when compared with nontreated areas. " 09/01/2008 - "The role of epidural phenol in cancer patients at the end of life." Order ALL the reference details at left...
3.	Typhoid Fever (Typhoid) 07/01/1942 - "Immunization against typhoid and paratyphoid with alcohol-killed, alcohol-preserved and heat-killed, phenol-preserved, vaccine." 09/24/1898 - "Treatment of Enteric Fever by Carbolic Acid at the British General Hospital, Nowshera, Punjab." 05/29/1897 - "The Treatment of Enteric Fever by Carbolic Acid." 06/24/1893 - "TYPHOID FEVER and its TREATMENT by the CARBOLIC ACID METHOD." 12/31/1892 - "NOTES on CARBOLIC ACID: its PHYSIOLOGICAL ACTION and THERAPEUTIC USE in TYPHOID FEVER." Order ALL the reference details at left...
4.	Infection 02/01/2012 - "An analytic study to validate a diagnostic test was carried out at the Institute of Gastroenterology in Havana, Cuba in adult patients of both sexes in whom chromoendoscopy was carried out with red phenol at 0.1% over the gastric mucosa for the detection of Helicobacter pylori infection between November 2008 and December 2010. " 04/04/2012 - "Endophyte infection can have zero, positive, or negative effect on phenol content depending on the endophyte strain." 02/01/2012 - "The staining dye with red phenol at 0.1% resulted in a useful method in the diagnosis of Helicobacter pylori infection in the gastric mucosa, it can be applied in our environment and has multiple advantages (topographic localization, avoids contamination and fast and immediate reading)." 02/01/2012 - "The sensibility of red phenol dye in the diagnosis of Helicobacter pylori infection in the patients studied was of 72.6% with a confidence interval (C.I.) of 95% (64.9 to 79.2%) and a specificity of 75.5% C.I. 95% (61.9 to 85.4%). " 02/01/2012 - "The staining with red phenol at 0.1% is included in the invasive tests for the diagnosis of Helicobacter pylori infection and of the reactive techniques. " Order ALL the reference details at left...
5.	Burns 11/01/1992 - "Controlled trial with all animals receiving all treatments applied to different cutaneous phenol burn sites. " 09/01/2012 - "Basing on obtained data, it is shown that the state of phenol in first layer is close to solid for adsorption on closed tubes and progressively approaches the state of supercooled liquid after tube opening and with the rise in burn-off." 01/01/2011 - "Out of 42 phenol burns patients, the total burn surface area (TBSA) of 22 cases were ≤ 5%, 10 cases' TBSA were 6% ∼ 10%, and 5 cases' > 20%. " 01/01/2011 - "The clinical data of 42 phenol burn cases admitted in our hospital from 1998 to 2010 were reviewed retrospectively. " 11/01/2010 - "A 42-year-old male presented with black urine, painless brownish dermal burns, and a strong carbolic acid odor. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Glycerol (Glycerine)
2.	Typhoid-Paratyphoid Vaccines (Typhoid Vaccines)
3.	Thymol
4.	Tetracycline (Achromycin)
5.	Ethanol (Ethyl Alcohol)
6.	Glucose (Dextrose)
7.	Acetone
8.	Paraffin
9.	xanthone
10.	Benzene (Benzole)

Related Therapies and Procedures

1.	Injections
2.	Curettage
3.	Sympathectomy (Sympathectomies)
4.	Cordotomy
5.	Spinal Injections

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