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Ramalin

from Antarctic lichen Ramalina terebrata; structure in first source

Also Known As:

gamma-glutamyl-N'-(2-hydroxyphenyl)hydrazide

Networked: 9 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Acidic Amino Acids: 44
    - Glutamates: 45
      - Ramalin: 9
  - Dicarboxylic Amino Acids: 20
    - Glutamates: 45
      - Ramalin: 9

Experts

1.	Lee, Hong-Kum: 4 articles (12/2016 - 01/2015)
2.	Pyo, Suhkneung: 4 articles (12/2016 - 01/2015)
3.	Yim, Joung-Han: 4 articles (12/2016 - 01/2015)
4.	Yim, Joung Han: 3 articles (10/2021 - 08/2017)
5.	Han, Se Jong: 2 articles (10/2021 - 08/2017)
6.	Hong, Ju-Mi: 2 articles (10/2021 - 08/2017)
7.	Kim, Il-Chan: 2 articles (10/2021 - 08/2017)
8.	Kim, Tai Kyoung: 2 articles (10/2021 - 08/2017)
9.	Jang, Yeon Jeong: 2 articles (12/2016 - 09/2016)
10.	Park, Bongkyun: 2 articles (09/2016 - 01/2015)

Related Diseases

1.	Atherosclerosis 01/01/2015 - "Our study provides insight into the mechanisms underlying ramalin activity and suggests that ramalin may be a potential therapeutic agent to modulate inflammation within atherosclerosis. "
2.	Colorectal Neoplasms (Colorectal Cancer) 08/17/2017 - "The main objective of this study was to evaluate the anticancer capacities of ramalin, a secondary metabolite from the Antarctic lichen Ramalina terebrata, in the human colorectal cancer cell line HCT116. " 08/17/2017 - "In addition, ramalin significantly inhibited the migration and invasion of colorectal cancer cells in a concentration-dependent manner. " 08/17/2017 - "Anticancer Activity of Ramalin, a Secondary Metabolite from the Antarctic Lichen Ramalina terebrata, against Colorectal Cancer Cells." 08/17/2017 - "Taken together, these data suggest that ramalin may be a therapeutic candidate for the targeted therapy of colorectal cancer."
3.	Obesity 09/25/2016 - "The present study also provides insight into the mechanisms underlying the anti-obesity activity of ramalin and suggests that ramalin has the potential to prevent obesity. " 09/25/2016 - "The aim of this study was to examine the anti-obesity effect and the mechanism of ramalin in 3T3-L1 preadipocytes and high fat diet (HFD)-induced obese mice. " 09/25/2016 - "Taken together, these results indicate that ramalin inhibits adipogenesis in 3T3-L1 preadipocytes and prevents HFD-induced obesity. "
4.	Inflammation (Inflammations) 01/01/2015 - "Our study provides insight into the mechanisms underlying ramalin activity and suggests that ramalin may be a potential therapeutic agent to modulate inflammation within atherosclerosis. "
5.	Neoplasms (Cancer) 03/01/2016 - "Therefore, autophagy appears to be activated as a protective mechanism against apoptosis in cancer cells exposed to ramalin. " 01/05/2022 - "This review focuses on the lichen-derived metabolite gyrophoric acid and other select secondary metabolites (e.g., usnic acid, salazinic acid, physodic acid, vulpinic acid ceratinalone, flavicansone, ramalin, physciosporin, tumidulin, atranorin, parmosidone) that modulate a number of cellular pathways relevant to several biomedical diseases and disorders, including cancer, diabetes and cardiovascular disease. " 01/01/2022 - "Atranorin, Lecanoric acid, Norstictic acid, Lobaric acid, Stictic acid, Ramalin, Gyrophoric acid, Salazinic acid, Protolichesterinic, and Fumarprotocetraric acid are some of the other purified lichen-metabolites with potent anti-cancer activities. "

Related Drugs and Biologics

1.	gyrophoric acid
2.	salazinic acid
3.	atranorin
4.	Dimethylnitrosamine (Nitrosodimethylamine)
5.	Antioxidants
6.	Antineoplastic Agents (Antineoplastics)
7.	norstictic acid
8.	stictic acid
9.	lobaric acid
10.	vulpinic acid

Related Therapies and Procedures

1.	Therapeutics
2.	Oral Administration