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North American Indian Childhood Cirrhosis

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Diamond-Blackfan Anemia (Anemia, Diamond Blackfan)
2.	Neoplasms (Cancer)
3.	Mandibulofacial Dysostosis (Treacher Collins Syndrome)
4.	Shwachman-Diamond Syndrome
5.	Bowen-Conradi syndrome

Experts

1.	Baserga, Susan J: 2 articles (01/2012 - 08/2010)
2.	Freed, Emily F: 2 articles (01/2012 - 08/2010)
3.	Fujii, Yoichi Robertus: 1 article (01/2018)
4.	McCann, Kathleen L: 1 article (01/2012)
5.	McStay, Brian: 1 article (01/2012)
6.	Prieto, José-Luis: 1 article (01/2012)
7.	Mitchell, Grant A: 1 article (12/2005)
8.	Richter, Andrea: 1 article (12/2005)
9.	Yu, Bin: 1 article (12/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to North American Indian Childhood Cirrhosis:

1.	Proteins (Proteins, Gene)FDA Link 08/01/2010 - "Recently, a missense mutation in the C-terminus of an SSU processome protein, Utp4/Cirhin, was reported to cause North American Indian childhood cirrhosis (NAIC). " 12/10/2005 - "Nucleolar localization of cirhin, the protein mutated in North American Indian childhood cirrhosis."
2.	RNA Precursors (Precursor, mRNA)IBA 01/01/2012 - "NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing."
3.	Ribosomal Proteins (Ribosomal Protein)IBA 01/01/2018 - "It is well known that ribosomopathies, such as Diamond-Blackfan anemia, dyskeratiosis congenital, Shwachman-Diamond syndrome, 5q-myelodysplastic syndrome, Treacher Collins syndrome, cartilage-hair hypoplasia, North American Indian childhood cirrhosis, isolated congenital asplenia, Bowen-Conradi syndrome and cancer are caused by altered expression of ribosomal proteins or rRNA genes. "

Therapies and Procedures

1.	Liver Transplantation 08/01/2022 - "First described by our group in 1981 and historically named North American Indian childhood cirrhosis, such a condition often requires liver transplantation during the pediatric age. "