13 Insulin-Dependent Diabetes Mellitus

Also Known As:

Diabetes Mellitus, Insulin-Dependent, 13; IDDM13; Insulin-Dependent Diabetes Mellitus 13

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Nutritional and Metabolic Diseases: 15
- Metabolic Diseases: 10142
  - Glucose Metabolism Disorders: 375
    - Diabetes Mellitus: 56563
      - Type 1 Diabetes Mellitus: 36799
        13 Insulin-Dependent Diabetes Mellitus: 7
Endocrine System Diseases: 968
- Diabetes Mellitus: 56563
  - Type 1 Diabetes Mellitus: 36799
    - 13 Insulin-Dependent Diabetes Mellitus: 7
Immune System Diseases: 4321
- Autoimmune Diseases: 34618
  - Type 1 Diabetes Mellitus: 36799
    - 13 Insulin-Dependent Diabetes Mellitus: 7

Related Diseases

1.	Type 1 Diabetes Mellitus (Autoimmune Diabetes)
2.	12 Insulin-Dependent Diabetes Mellitus
3.	Genetic Predisposition to Disease (Genetic Predisposition)
4.	7 Insulin-Dependent Diabetes Mellitus
5.	Glucose Intolerance

Experts

1.	Carleu, L: 1 article (04/2002)
2.	Chung, W K: 1 article (04/2002)
3.	Gulko, P S: 1 article (04/2002)
4.	Hodge, S E: 1 article (04/2002)
5.	Jackson, T: 1 article (04/2002)
6.	Slager, S L: 1 article (04/2002)
7.	Winchester, R J: 1 article (04/2002)
8.	Concannon, P: 1 article (10/2001)
9.	Cox, N J: 1 article (10/2001)
10.	Johnson, L: 1 article (10/2001)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to 13 Insulin-Dependent Diabetes Mellitus:

1.	Insulin (Novolin)FDA Link 04/01/1998 - "The present state of knowledge and controversies about the etiopathogenesis of tyep 1 diabetes can be summarized as follows: MHC class II genes (IDDM1) confer the strongest susceptibility with a hierachy DQ > DR; more than ten other chromosome regions (IDDM2 to IDDM13) have been identified as candidates for linkage with type 1 diabetes: currently, there is consensus for insulin (IDDM2) and a few other loci, while the remainder await confirmation. " 01/01/1999 - "IDDM12 (CTLA4) on 2q33 and IDDM13 on 2q34 in genetic susceptibility to type 1 diabetes (insulin-dependent)."
2.	Glucose (Dextrose)FDA LinkGeneric 05/01/1995 - "Twenty-seven (30%) of the women with previous GDM had abnormal glucose tolerance at follow-up (2 had insulin-dependent diabetes mellitus, 13 had non-insulin-dependent diabetes mellitus, and 12 had impaired glucose tolerance). " 06/01/1998 - "To test whether the growth phenotype of cells from patients with diabetic nephropathy was related to a lack of protection from oxidative stress, the effect of reduced glutathione (GSH) on cultured skin fibroblasts from 13 insulin-dependent diabetes mellitus (IDDM) patients with nephropathy (DN), 10 IDDM patients without kidney disease (D), and 10 nondiabetic control subjects (C), in normal (5 mM) glucose (NG) and high (22 mM) glucose (HG) medium was studied. "
3.	Interleukin-1 (Interleukin 1)IBA 11/01/1998 - "Genetic analysis of chromosome 2 in type 1 diabetes: analysis of putative loci IDDM7, IDDM12, and IDDM13 and candidate genes NRAMP1 and IA-2 and the interleukin-1 gene cluster. "
4.	Glutathione (Reduced Glutathione)IBA 06/01/1998 - "To test whether the growth phenotype of cells from patients with diabetic nephropathy was related to a lack of protection from oxidative stress, the effect of reduced glutathione (GSH) on cultured skin fibroblasts from 13 insulin-dependent diabetes mellitus (IDDM) patients with nephropathy (DN), 10 IDDM patients without kidney disease (D), and 10 nondiabetic control subjects (C), in normal (5 mM) glucose (NG) and high (22 mM) glucose (HG) medium was studied. "
5.	Insulin-Like PeptidesIBA 04/01/2002 - "The IDDM13 region containing the insulin-like growth factor binding protein-5 (IGFBP5) gene on chromosome 2q33-q36 and the genetic susceptibility to rheumatoid arthritis."
6.	P-2 (P 2)IBA 10/01/2001 - "Three chromosome regions were identified that showed significant evidence of linkage (P<2.2x10(-5); LOD scores >4), 6p21 (IDDM1), 11p15 (IDDM2), 16q22-q24, and four more that showed suggestive evidence (P<7.4x10(-4), LOD scores > or =2.2), 10p11 (IDDM10), 2q31 (IDDM7, IDDM12, and IDDM13), 6q21 (IDDM15), and 1q42. "