Pulmonary Arteriovenous Fistulas

A rare finding that occurs in patients with HEREDITARY HEMORRHAGIC TELANGIECTASIA (OMIM: 187300), although the fistulas themselves are hereditary in only a small minority of cases. Onset is typically in adolescence. OMIM: 265140

Networked: 35 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Cyanosis
2.	Hypoxia (Hypoxemia)
3.	Heterotaxy Syndrome
4.	Brain Abscess (Abscess, Brain)
5.	Arteriovenous Fistula

Experts

1.	Akkan, Koray: 1 article (01/2021)
2.	Aslan, Ayse Tana: 1 article (01/2021)
3.	Onay, Zeynep Reyhan: 1 article (01/2021)
4.	Ramasli Gursoy, Tugba: 1 article (01/2021)
5.	Sismanlar Eyuboglu, Tugba: 1 article (01/2021)
6.	Dai, Ting-Jun: 1 article (05/2020)
7.	Gao, Lu-Yao: 1 article (05/2020)
8.	Xu, Guang-Run: 1 article (05/2020)
9.	Asada, Dai: 1 article (02/2020)
10.	Ikeda, Kazuyuki: 1 article (02/2020)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pulmonary Arteriovenous Fistulas:

1.	Oxygen (Dioxygen)IBA 02/01/2006 - "Findings demonstrated the presence of multiple pulmonary arteriovenous fistulas resulting in oxygen desaturation owing to shunting (PaO2, 44 mm Hg). " 02/01/1977 - "Intrapulmonary shunt measured in the sitting position by the oxygen breathing method increased at total lung capacity in 7 of 8 patients with pulmonary arteriovenous fistulas. " 01/01/2011 - "A 19-year-old male patient presented cyanosis and dyspnoea because of the presence of multiple pulmonary arteriovenous fistulas resulting in oxygen desaturation. "
2.	TungstenIBA 03/01/1997 - "[Rendu-Osler-Weber disease: embolization of pulmonary arteriovenous fistulas with tungsten coils. "
3.	Radioisotopes (Radionuclides)IBA 04/01/1975 - "Multiple pulmonary arteriovenous fistulas demonstrated by dynamic radionuclide pulmonary perfusion scanning." 04/01/1975 - "Dynamic radionuclide perfusion scintigraphy performed with 99mTc-labeled microspheres was instrumental in establishing the diagnosis of multiple, small-vessel, pulmonary arteriovenous fistulas in a 14-month-old patient with cyanosis. "
4.	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/01/2008 - "Use of sildenafil and nitric oxide in the management of hypoxemia owing to pulmonary arteriovenous fistulas after total cavopulmonary connection."
5.	Sildenafil Citrate (Viagra)FDA Link 02/01/2008 - "Use of sildenafil and nitric oxide in the management of hypoxemia owing to pulmonary arteriovenous fistulas after total cavopulmonary connection."
6.	N-(3,4,5-trichlorophenyl)succinimideIBA 12/01/2000 - "A high incidence of pulmonary arteriovenous fistulas (PAVF) has been reported after bidirectional cavopulmonary shunt (BCPS) or total cavopulmonary shunt (TCPS; BCPS in patients with interrupted inferior vena cava). "
7.	neodymium pyrocatechin disulfonate (NPD)IBA 01/01/2021 - "In the present case, both hepatopulmonary syndrome (HPS) and pulmonary arteriovenous fistulas (PAVFs) developed in a child with NPD and were successfully treated with repeated embolization. "

Therapies and Procedures

1.	Right Heart Bypass (Cavopulmonary Anastomosis) 08/01/2009 - "The cause of pulmonary arteriovenous fistulas after a cavopulmonary anastomosis is not clearly known, but the previous studies regarding their causes have been focused mainly on the hepatic factors. " 02/01/2020 - "Bubble contrast echocardiography might be highly false positive in detecting pulmonary arteriovenous fistulas in patients with cavopulmonary anastomosis. " 02/01/2020 - "Development of pulmonary arteriovenous fistulas in patients with cavopulmonary anastomosis may result in a significant morbidity. " 01/01/1996 - "This case demonstrates that pulmonary arteriovenous fistulas (PAVFs) may develop rapidly after cavopulmonary anastomosis in young infants. " 01/01/1996 - "Fulminant development of pulmonary arteriovenous fistulas in an infant after total cavopulmonary shunt."
2.	Fontan Procedure (Fontan Operation) 06/01/2017 - "We describe a case involving a successful Fontan procedure for the treatment of pulmonary arteriovenous fistulas in a patient with polysplenia. " 06/01/2017 - "Fontan operation with bilateral conduits for the treatment of pulmonary arteriovenous fistulas in a patient with polysplenia after reconstruction of a non-confluent pulmonary artery." 12/01/2000 - "Development of pulmonary arteriovenous fistulas after bidirectional cavopulmonary shunt." 07/01/1998 - "The development of pulmonary arteriovenous fistulas after bidirectional cavopulmonary operations, such as the bidirectional Glenn shunt and Kawashima's procedure, has raised concern. " 05/01/2011 - "During the follow-up period, most surviving patients showed good functional status without common late complications of the Fontan procedure such as, recurrent cyanosis, pulmonary arteriovenous fistulas, chronic arrhythmias, and SVC syndrome. "
3.	Therapeutic Embolization 01/01/1993 - "A case of pulmonary arteriovenous fistulas (PAVF) treated with detachable balloon embolotherapy is reported. " 01/01/1993 - "[A case of pulmonary arteriovenous fistulas (PAVF) treated with detachable balloon embolotherapy]." 02/01/1980 - "Therapeutic embolization of pulmonary arteriovenous fistulas is described as an alternate method of treatment for patients with diffuse pulmonary involvement in whom resection is not feasible." 12/01/1990 - "We report a 27-year-old woman with multiple pulmonary arteriovenous fistulas who required coil spring embolotherapy in her 24th week of pregnancy due to a spontaneous hemothorax and hypoxemia." 10/01/1990 - "Therapeutic embolization of pulmonary arteriovenous fistulas was performed for the prevention against brain abscess and improvement of hypoxia."
4.	Catheters 01/01/1992 - "Catheter embolization of pulmonary arteriovenous fistulas in an infant." 11/01/2008 - "Catheter interventions in miscellaneous lesions in CHD: ruptured sinus of Valsalva, coronary arteriovenous fistulas, and pulmonary arteriovenous fistulas."
5.	Sternotomy 01/01/2002 - "[A case report of bilateral multiple pulmonary arteriovenous fistulas treated surgically at one-stage procedure by median sternotomy]." 04/01/1983 - "A 1-year-old girl with diffuse pulmonary arteriovenous fistulas associated with left isomerism was not considered a good candidate for operation after an exploratory sternotomy. "