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10-acetylirciformonin B

from the sponge Ircinia sp.; structure in first source

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - 10-acetylirciformonin B: 2

Experts

1.	Chen, Huei-Mei: 2 articles (05/2014 - 10/2012)
2.	Chen, Yu-Cheng: 2 articles (05/2014 - 10/2012)
3.	El-Shazly, Mohamed: 2 articles (05/2014 - 10/2012)
4.	Lu, Mei-Chin: 2 articles (05/2014 - 10/2012)
5.	Su, Jui-Hsin: 2 articles (05/2014 - 10/2012)
6.	Chang, Chao-Yuan: 1 article (05/2014)
7.	Juan, Yung-Shun: 1 article (05/2014)
8.	Shih, Huei-Chuan: 1 article (05/2014)
9.	Shih, Shou-Ping: 1 article (05/2014)
10.	Wu, Yang-Chang: 1 article (05/2014)

Related Diseases

1.	Leukemia 10/09/2012 - "The purpose of this study was to investigate the cytotoxic effects of 10-acetylirciformonin B and its possible mechanism of action against leukemia HL 60 cells. " 10/09/2012 - "10-acetylirciformonin B, a sponge furanoterpenoid, induces DNA damage and apoptosis in leukemia cells." 05/22/2014 - "A marine furanoterpenoid derivative, 10-acetylirciformonin B (10AB), was found to inhibit the proliferation of leukemia, hepatoma, and colon cancer cell lines, with selective and significant potency against leukemia cells. "
2.	Mitochondrial Diseases (Mitochondrial Disease) 05/22/2014 - "Cracking the cytotoxicity code: apoptotic induction of 10-acetylirciformonin B is mediated through ROS generation and mitochondrial dysfunction."
3.	Neoplasms (Cancer) 10/09/2012 - "10-Acetylirciformonin B, a furanoterpenoid derived from irciformonin B found in a marine sponge, has been reported to possess potent cytotoxic activity against several cancer cell lines. "
4.	Hepatocellular Carcinoma (Hepatoma) 05/22/2014 - "A marine furanoterpenoid derivative, 10-acetylirciformonin B (10AB), was found to inhibit the proliferation of leukemia, hepatoma, and colon cancer cell lines, with selective and significant potency against leukemia cells. "
5.	Colonic Neoplasms (Colon Cancer) 05/22/2014 - "A marine furanoterpenoid derivative, 10-acetylirciformonin B (10AB), was found to inhibit the proliferation of leukemia, hepatoma, and colon cancer cell lines, with selective and significant potency against leukemia cells. "