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glutathione-C4

a butanoyl GSH derivative with potent anti-influenza activity

Also Known As:

GSH-C4

Networked: 7 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Glutathione: 14524
      - glutathione-C4: 7

Experts

1.	Fraternale, Alessandra: 5 articles (05/2019 - 08/2011)
2.	Magnani, Mauro: 5 articles (05/2019 - 08/2011)
3.	Palamara, Anna Teresa: 4 articles (05/2019 - 08/2011)
4.	Checconi, Paola: 3 articles (05/2019 - 01/2019)
5.	Amatore, Donatella: 2 articles (05/2019 - 08/2011)
6.	Coluccio, Paolo: 2 articles (05/2019 - 08/2011)
7.	Nencioni, Lucia: 2 articles (05/2019 - 08/2011)
8.	Baldelli, Sara: 2 articles (01/2019 - 01/2019)
9.	Ciriolo, Maria Rosa: 2 articles (01/2019 - 01/2019)
10.	De Chiara, Giovanna: 2 articles (01/2019 - 01/2019)

Related Diseases

1.	Rosacea (Acne Rosacea) 04/01/2021 - "ANTERA 3D photographs confirmed the positive evolution observed clinically with a significant reduction (-24%) in hemoglobin content: from 1.88 at baseline to 1.44 at week 8. This new GSH-C4, beta-glycyrrethic and azelaic acids cream has shown to be efficacious in mild to moderate rosacea subjects. "
2.	Infections 05/01/2019 - "In conclusion, GSH-C4 treatment could be used in the elderly to contrast influenza virus infection by inducing immune response, in particular the Th1 profile." 05/01/2019 - "In contrast, PDI expression was upregulated during infection and appeared counterbalanced by GSH-C4. " 05/01/2019 - "Following infection, GSH content remained low and neither infection nor GSH-C4 treatment affected Nrf2 expression. " 08/01/2011 - "The aim of this study was to determine whether GSH-C4, a hydrophobic glutathione derivative, affects in vitro and in vivo influenza virus infection by interfering with redox-sensitive intracellular pathways involved in the maturation of viral hemagglutinin (HA). "
3.	Inflammation (Inflammations) 01/01/2019 - "Corrigendum: GSH-C4 Acts as Anti-inflammatory Drug in Different Models of Canonical and Cell Autonomous Inflammation Through NFκB Inhibition." 01/01/2019 - "We found that inflammation was paralleled by a strong induction of the phosphorylated form of NFκB, which translocates into the nucleus; a process that was also efficiently inhibited by the treatment with GSH-C4. " 01/01/2019 - "GSH-C4 Acts as Anti-inflammatory Drug in Different Models of Canonical and Cell Autonomous Inflammation Through NFκB Inhibition."
4.	Virus Diseases (Viral Diseases) 08/01/2014 - "The two antiviral drugs tested were acyclovir (ACV), commonly used to treat herpes virus infections, and an N-butanoyl glutathione (GSH) derivative, GSH-C4. "
5.	Seborrheic Dermatitis 01/01/2019 - "The Effectiveness of a New Topical Formulation Containing GSH-C4 and Hyaluronic Acid in Seborrheic Dermatitis: Preliminary Results of an Exploratory Pilot Study."

Related Drugs and Biologics

1.	Hemoglobins (Hemoglobin)
2.	Acids
3.	Glutathione (Reduced Glutathione)
4.	Viral Hemagglutinins
5.	Hyaluronic Acid (Hyaluronan)
6.	Antiviral Agents (Antivirals)
7.	Acyclovir (Aciclovir)