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NVC-422

structure in first source

Also Known As:

N,N-dichloro-2,2-dimethyltaurine

Networked: 9 relevant articles (4 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Acyclic Hydrocarbons
    - Alkanes: 241
      - Alkanesulfonic Acids
        Taurine: 3452
        NVC-422: 9
- Sulfur Compounds: 278
  - Sulfur Acids
    - Sulfonic Acids: 1605
      - Alkanesulfonic Acids
        Taurine: 3452
        NVC-422: 9

Experts

1.	Anderson, Mark: 6 articles (05/2013 - 08/2011)
2.	Debabov, Dmitri: 6 articles (02/2013 - 06/2011)
3.	Wang, Lu: 5 articles (05/2013 - 06/2011)
4.	Jekle, Andreas: 4 articles (02/2013 - 12/2011)
5.	Memarzadeh, Bahram: 3 articles (05/2013 - 08/2011)
6.	Celeri, Chris: 3 articles (02/2013 - 06/2011)
7.	Zuck, Meghan: 3 articles (02/2013 - 12/2011)
8.	Khosrovi, Behzad: 3 articles (12/2011 - 06/2011)
9.	Stroman, David: 2 articles (01/2022 - 02/2013)
10.	Xu, Ping: 2 articles (02/2013 - 06/2011)

Related Diseases

1.	Infections 05/01/2013 - "The antifungal efficacy of NVC-422 was investigated using a guinea pig model of infection with Trichophyton mentagrophytes. " 05/01/2013 - "Clinical evaluation of NVC-422 in the treatment of superficial infections caused by dermatophytes, including onychomycosis, is warranted." 12/01/2012 - "N-chlorotaurine and its analogues N,N-dichloro-2,2-dimethyltaurine and N-monochloro-2,2-dimethyltaurine are safe and effective bactericidal agents in ex vivo corneal infection models."
2.	Rhinosinusitis 07/01/2012 - "The aim of this study was to investigate the safety and efficacy of NVC-422 as local antibiofilm treatment in a sheep model of rhinosinusitis. "
3.	Wounds and Injuries (Trauma) 06/01/2011 - "Treatment of the infected granulating wound with NVC-422 resulted in significant reduction of the bacterial tissue burden and faster wound healing compared to a saline-treated control. "
4.	Tinea (Ringworm) 05/01/2013 - "Evaluation of the efficacy of NVC-422 in the treatment of dermatophytosis using an experimental guinea pig model showed that this compound possesses potent antifungal efficacy as measured by mycological and clinical endpoints. " 05/01/2013 - "Efficacy of NVC-422 in the treatment of dermatophytosis caused by Trichophyton mentagrophytes using a guinea pig model."
5.	Sinusitis 07/01/2012 - "Efficacy of NVC-422 against Staphylococcus aureus biofilms in a sheep biofilm model of sinusitis."

Related Drugs and Biologics

1.	N-monochloro-2,2-dimethyltaurine
2.	N-chlorotaurine
3.	Anticoagulants

Related Therapies and Procedures

1.	Catheters