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austocystin D

a potent and selectively cytotoxic compound from Aspergillus isolate UGM218; structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Aflatoxins: 1770
        austocystin D: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Aflatoxins: 1770
        austocystin D: 2
Biological Factors: 2472
- Biological Toxins: 20
  - Mycotoxins: 1745
    - Aflatoxins: 1770
      - austocystin D: 2

Experts

1.	Gu, Lei: 1 article (01/2021)
2.	Jiang, Chunhui: 1 article (01/2021)
3.	Liu, Ye: 1 article (01/2021)
4.	Wen, Siyuan: 1 article (01/2021)
5.	Xu, Chunjie: 1 article (01/2021)
6.	Arefolov, Alexander: 1 article (04/2011)
7.	Clardy, Jon: 1 article (04/2011)
8.	Clarke, Astrid S: 1 article (04/2011)
9.	Ishihara, Keiko: 1 article (04/2011)
10.	Marks, Kevin M: 1 article (04/2011)

Related Diseases

1.

Neoplasms (Cancer)

01/01/2021 - "FBXL5 was correlated significantly with austocystin d and bafilomycin and played an important role in anti-tumor and immunotherapy. "
04/25/2011 - "Here we show that the selective cytotoxic action of austocystin D arises from its selective activation by cytochrome P450 (CYP) enzymes in specific cancer cell lines, leading to induction of DNA damage in cells and in vitro. "

Related Drugs and Biologics

1.	Enzymes
2.	Cytochrome P-450 Enzyme System (Cytochrome P450)

Related Therapies and Procedures

1.	Immunotherapy