A hereditary form of intestinal polyposis where POLYPS first appear by age 20. Diagnosis is based on the presence of HARMATOMA - like gastrointestinal polyps that become malignant lesions by age 35 in 20% of cases. Germline mutations in the SMAD4 and BMPR1A genes have been identified. OMIM: 174900
Also Known As:
Bmpr1a-Related Juvenile Polyposis; Juvenile Polyposis Coli; Juvenile Polyposis Of Infancy; Juvenile Polyposis Of Stomach; Juvenile Polyposis, Infantile; Juvenile intestinal polyposis; Polyposis, familial, of entire gastrointestinal tract; Polyposis, juvenile intestinal; Smad4-Related Juvenile Polyposis