Disks Large Homolog 4 Protein

A neuronal protein consisting of three PDZ DOMAINS, an SH3 DOMAIN, and a C-terminal guanylate kinase-like region (see MAGUK PROTEINS). It localizes to the POST-SYNAPTIC DENSITY and associates with the cytoplasmic tail of NMDA RECEPTORS and SHAKER POTASSIUM CHANNELS, playing a critical role in NMDA receptor-mediated SYNAPTIC PLASTICITY.

Also Known As:

Discs Large Homolog 4 Protein; PSD-95 Protein; PSD95 Protein; Postsynaptic Density Protein 95; SAP-90 Protein; SAP90 Protein; Synapse-Associated Protein 90; PSD 95 Protein; SAP 90 Protein; Synapse Associated Protein 90

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Phosphate Group Acceptor)
        Guanylate Kinases: 106
        Disks Large Homolog 4 Protein: 94
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Disks Large Homolog 4 Protein: 94
  - Intracellular Signaling Peptides and Proteins: 32
    - Disks Large Homolog 4 Protein: 94
  - Nerve Tissue Proteins: 2
    - Disks Large Homolog 4 Protein: 94
- Peptides: 82426
  - Intracellular Signaling Peptides and Proteins: 32
    - Disks Large Homolog 4 Protein: 94

rat Dlg4 protein

Bio-Agent Context: Research Results