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nukacin ISK-1

a lantibiotic isolated from Staphyococcus warneri; amino acid sequence in first source

Also Known As:

nukacin 3299

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Pore Forming Cytotoxic Proteins
      - Bacteriocins: 556
        nukacin ISK-1: 3
  - Bacterial Proteins: 394
    - Bacteriocins: 556
      - nukacin ISK-1: 3

Experts

1.	Nakayama, Jiro: 2 articles (12/2015 - 04/2010)
2.	Shioya, Kouki: 2 articles (12/2015 - 04/2010)
3.	Sonomoto, Kenji: 2 articles (12/2015 - 04/2010)
4.	Nagao, Jun-Ichi: 1 article (12/2015)
5.	Nishie, Mami: 1 article (12/2015)
6.	Noguchi, Megumi: 1 article (12/2015)
7.	Shimafuji, Chinatsu: 1 article (12/2015)
8.	Zendo, Takeshi: 1 article (12/2015)
9.	Bastos, Maria do Carmo de Freire: 1 article (11/2010)
10.	Ceotto, Hilana: 1 article (11/2010)

Related Diseases

1.	Dehydration (Water Stress) 12/01/2015 - "NukM, the modifying enzyme of nukacin ISK-1, which is produced by Staphylococcus warneri ISK-1, catalyzes the dehydration of specific Ser/Thr residues in a precursor peptide, followed by conjugative addition of intramolecular Cys to dehydrated residues to generate a cyclic structure. " 04/01/2010 - "The nukacin ISK-1 prepeptide (NukA) undergoes posttranslational modifications, such as the dehydration and cyclization reactions required to form the unusual amino acids by the modification enzyme NukM. "
2.	Bovine Mastitis 11/20/2010 - "Nukacin 3299 exhibited activity towards staphylococcal strains involved in bovine mastitis, showing a potential application on mastitis control, a disease with great economic impact." 11/20/2010 - "Nukacin 3299 (formerly designated simulancin 3299), produced by a Staphylococcus simulans strain involved in bovine mastitis in Brazil, is the first peptide bacteriocin described in this staphylococcal species. "
3.	Mastitis 11/20/2010 - "Nukacin 3299 exhibited activity towards staphylococcal strains involved in bovine mastitis, showing a potential application on mastitis control, a disease with great economic impact."

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Enzymes
3.	Bacteriocins (Lantibiotics)
4.	Amino Acids