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Ro 25-6760
Also Known As:
1,25-dihydroxy-16-ene-23-yne-26,27--hexafluoro-19-nor-cholecalciferol
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Polycyclic Compounds: 6
Fused-Ring Compounds
Steroids: 70059
Secosteroids: 22
Vitamin D: 33265
Cholecalciferol: 4786
Ro 25-6760: 3
Cholestanes
Sterols: 2245
Cholecalciferol: 4786
Ro 25-6760: 3
Cholestenes
Cholecalciferol: 4786
Ro 25-6760: 3
Lipids: 114793
Membrane Lipids: 1591
Sterols: 2245
Cholecalciferol: 4786
Ro 25-6760: 3
Related Diseases
1.
Prostatic Neoplasms (Prostate Cancer)
03/01/1999 - "
1alpha,25-Dihydroxyvitamin D3 (1alpha,25(OH)2D3) and its synthetic analogue, Ro 25-6760, have an antiproliferative effect on some prostate cancer cell lines.
"
2.
Neoplasms (Cancer)
11/01/1998 - "
three times/week did not cause any significant tumor growth delay, whereas synthetic analogue Ro 25-6760, at both concentrations, caused a significant tumor growth inhibition in comparison with the control arm.
"
11/01/1998 - "
However, both 1,25-dihydroxyvitamin D3 or Ro 25-6760 had no growth inhibitory effect at all applied concentrations in mice with the SW-620 tumor xenografts.
"
3.
Breast Neoplasms (Breast Cancer)
05/01/1998 - "
The antiproliferative effect of 1,25-dihydroxycholecalciferol (Ro 21-5535) and of the two non hypercalcemic analogs (1a,25-dihydroxy-16-ene-23-yne-26,27-hexafluorocholecalciferol+ ++, Ro 24-5531 and 1a,25-dihydroxy-16-ene-23-yne-26,27-hexafluoro-19-nor-cholec alciferol, Ro 25-6760) was studied in MCF-7 and MDAMB-468 human breast cancer cell lines.
"
Related Drugs and Biologics
1.
Calcitriol (Calcijex)
2.
Ro 24-5531
3.
hydroxide ion