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EDNsFv anti-transferrin receptor
human recombinant eosinophil-derived neurotoxin fused to sFv, a single chain antibody; amino acid sequence known
Also Known As:
EDNsFv; EDNsFv anti-transferrin receptors; anti-transferrin receptor, EDNsFv
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Proteins: 496323
Blood Proteins: 12679
Serum Globulins: 555
Immunoglobulins: 30911
Immunoglobulin Fragments: 979
Immunoglobulin Fab Fragments: 766
Immunoglobulin Variable Region: 208
Single-Chain Antibodies: 865
EDNsFv anti-transferrin receptor: 1
Immunoproteins: 43
Immunoglobulins: 30911
Antibodies: 135587
Monoclonal Antibodies: 57170
Single-Chain Antibodies: 865
EDNsFv anti-transferrin receptor: 1
Immunoglobulin Fragments: 979
Immunoglobulin Fab Fragments: 766
Immunoglobulin Variable Region: 208
Single-Chain Antibodies: 865
EDNsFv anti-transferrin receptor: 1
Globulins: 3119
Serum Globulins: 555
Immunoglobulins: 30911
Immunoglobulin Fragments: 979
Immunoglobulin Fab Fragments: 766
Immunoglobulin Variable Region: 208
Single-Chain Antibodies: 865
EDNsFv anti-transferrin receptor: 1
Recombinant Proteins: 2811
Recombinant Fusion Proteins: 337
EDNsFv anti-transferrin receptor: 1
Peptides: 84029
Peptide Fragments: 379
Immunoglobulin Fragments: 979
Immunoglobulin Fab Fragments: 766
Immunoglobulin Variable Region: 208
Single-Chain Antibodies: 865
EDNsFv anti-transferrin receptor: 1
Related Diseases
1.
Neoplasms (Cancer)
10/28/1994 - "
In contrast to rEDN that had no inherent cytotoxicity to human tumor cells, the EDNsFv fusion protein was cytotoxic to human leukemia cells that express the human transferrin receptor with an IC50, 0.2-1 nM. At 1.3 nM EDNsFv, no cytotoxicity was observed on cells that lack the human transferrin receptor.
"
2.
Leukemia
10/28/1994 - "
In contrast to rEDN that had no inherent cytotoxicity to human tumor cells, the EDNsFv fusion protein was cytotoxic to human leukemia cells that express the human transferrin receptor with an IC50, 0.2-1 nM. At 1.3 nM EDNsFv, no cytotoxicity was observed on cells that lack the human transferrin receptor.
"
Related Drugs and Biologics
1.
Transferrin Receptors (Transferrin Receptor)
2.
Proteins (Proteins, Gene)