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CTC 96

promotes wart growth in papillomavirus-infected rabbits; may help prevent herpes simplex 2 virus infection if applied vaginally

Also Known As:

CTC-96; Doxovir

Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organometallic Compounds: 64
  - CTC 96: 4

Experts

1.	Asbell, Penny A: 1 article (06/2006)
2.	Epstein, Seth P: 1 article (06/2006)
3.	Gershon, David: 1 article (06/2006)
4.	Kristic, Katarina J: 1 article (06/2006)
5.	Pashinsky, Yevgenia Y: 1 article (06/2006)
6.	Srivilasa, Charlie: 1 article (06/2006)
7.	Winicov, Irene: 1 article (06/2006)
8.	Lium, E K: 1 article (05/2001)
9.	Schwartz, J A: 1 article (05/2001)
10.	Silverstein, S J: 1 article (05/2001)

Related Diseases

1.	Keratoconjunctivitis 06/05/2006 - "Efficacy of topical cobalt chelate CTC-96 against adenovirus in a cell culture model and against adenovirus keratoconjunctivitis in a rabbit model."
2.	Infections 05/01/2001 - "Collectively, these experiments suggest that CTC-96 is a broad-spectrum inhibitor of infection by enveloped viruses and that it inhibits HSV-1 infection at the point of membrane fusion independent of the type of virus and cellular receptors present." 05/01/2001 - "The experiments described here identify the stage in the virus life cycle where CTC-96 acts and demonstrate that the drug inhibits infection of susceptible cells. " 05/01/1994 - "Following experimental infection of domestic rabbits with CRPV, CTC-96 was applied to infection sites twice daily, 5 days a week for a total of 8 weeks. " 05/01/2001 - "This observation was supported by the failure to detect the accumulation of virus-specified proteins and alpha mRNA transcripts when CTC-96 is present at the onset of infection. "
3.	Vesicular Stomatitis 05/01/2001 - "Furthermore, CTC-96 inhibits plaque formation by varicella-zoster virus and vesicular stomatitis virus as efficiently as by HSV-1. "
4.	Warts (Wart) 05/01/1994 - "Topical CTC-96 accelerates wart growth in rabbits infected with cottontail rabbit papillomavirus."
5.	Neoplasms (Cancer) 05/01/1994 - "With increasing dose of CTC-96 we observed tumors earlier, larger, and more often across eight infected sites on each animal." 05/01/1994 - "CTC-96, a cobalt containing complex, was tested as a putative topical therapeutic agent for the treatment of papillomavirus-induced tumors in our cottontail rabbit papillomavirus (CRPV)-rabbit model system. "

Related Drugs and Biologics

1.	Cobalt
2.	CTC 96
3.	Trifluridine (Viroptic)
4.	Messenger RNA (mRNA)
5.	Proteins (Proteins, Gene)
6.	Antiviral Agents (Antivirals)